Publications

since 2003

2016

  • Ricarda A. Busse , Andreea Scacioc , Amanda M. Schalk , Roswitha Krick , Michael Thumm , Karin Kühnel (2016) Analyzing Protein-Phosphoinositide Interactions with Liposome Flotation Assays. Methods Mol Biol 1376, 155–162 

2015

  • Juris L, Montino M, Rube P, Schlotterhose P, Thumm M and Krick R (2015) PI3P binding by Atg21 organizes Atg8 lipidation. EMBO J. 34: 955–973 

  • Busse, R. A., Scacioc, A., Krick, R., Perez-Lara, A., Thumm, M. and Kühnel, K. (2015). Characterization of PROPPIN-Phosphoinositide Binding and Role of Loop 6CD in PROPPIN-Membrane Binding. Biophysical Journal, 108(9), 2223–2234.

  • Thumm, M. and Simons, M. (2015) Myelinophagy: Schwann cells dine in. The Journal of Cell Biology, 210(1), 9–10

2013

  • Welter, E., Montino, M., Reinhold, R., Schlotterhose, P., Krick, R., Dudek, J., Rehling, P., Thumm ,M. (2013), Uth1 is a mitochondrial inner membrane protein dispensable for post-log phase and rapamycin-induced mitophagy. FEBS J. 280, 4970-4982

  • Busse RA, Scacioc A, Hernandez JM, Krick R, Stephan M, Janshoff A, Thumm M & Kühnel K (2013), Qualitative and quantitative characterization of protein-phosphoinositide interactions with liposome-based methods.. Autophagy 9, 770-777

  • Thumm M, Busse RA, Scacioc A, Stephan M, Janshoff A, Kühnel K & Krick R (2013), It takes two to tango: PROPPINs use two phosphoinositide-binding sites.. Autophagy 9, 106-107

2012

  • Roswitha Krick, Ricarda A Busse, Andreea Scacioc, Milena Stephan, Andreas Janshoff, Michael Thumm*, and Karin Kühnel* *corresponding author (2012), Structural and functional characterization of the two phosphoinositide binding sites of PROPPINs, a β-propeller protein family. PNAS 109(30), E2042-9

  • Klionsky DJ et al. (2012), Guidelines for the use and interpretation of assays for monitoring autophagy. AUTOPHAGY 8, 4, 445-544

2011

  • Thumm M. und Klionsky, D.J. (2011), New thoughts regarding Atg8 and ubiquitination. Autophagy. 7, (2), 125-6

  • Krick R, Bremer S, Welter E, Eskelinen EL, Thumm M. (2011), Cheating on ubiquitin with Atg8. Autophagy. 7, (2),

  • Usha Nair, Michael Thumm*, Daniel J Klionsky*, and Roswitha Krick * corresponding author (2011), GFP-Atg8 protease protection as a tool to monitor autophagosome biogenesis. AUTOPHAGY 7 (12), 1546-1550

  • Daniel J Klionsky, Eric H Baehrecke, John H Brumell, Charleen T Chu, Patrice Codogno, Ana Marie Cuervo, Jayanta Debnath, Vojo Deretic, Zvulun Elazar, Eeva-Liisa Eskelinen, Steven Finkbeiner, Juan Fueyo-Margareto, David Gewirtz, Marja Jäättelä, Guido Kroemer, Beth Levine, Thomas J Melia, Noboru Mizushima, David C Rubinsztein, Anne Simonsen, Andrew Thorburn, Michael Thumm, and Sharon A Tooze (2011), A comprehensive glossary of autophagy-related molecules and processes (2 (nd) edition). AUTOPHAGY 7(11), 1273-1294

2010

  • Klionsky DJ, Codogno P, Cuervo AM, Deretic V, Elazar Z, Fueyo-Margareto J, Gewirtz DA, Kroemer G, Levine B, Mizushima N, Rubinsztein DC, Thumm M, Tooze SA (2010), A comprehensive glossary of autophagy-related molecules and processes.. Autophagy 6, 4, 438-448

  • E.Welter, M.Thumm* and R.Krick (2010), Quantification of nonselective bulk autophagy in S. cerevisiae using Pgk1-GFP. Autophagy 6, (6), 794-797

  • R.Krick*, S.Bremer*, E.Welter*, P.Schlotterhose, Y.Muehe, E.-L.Eskelinen and M.Thumm (2010), Cdc48/p97 and Shp1/p47 regulate autophagosome biogenesis in concert with ubiquitin-like Atg8. J. Cell Biol. 190, 6, 965-973

2009

  • R. Krick, Y. Mühe, T. Prick, M. Bredschneider, S. Bremer, D. Wenzel, E.-L. Eskelinen, and M. Thumm (2009), Micronucleophagy: Genetic and morphological traits. Autophagy, 5, (2), 270-272

  • Jean Claude Farré, Roswitha Krick, Suresh Subramani, Michael Thumm (2009), Turnover of organelles by autophagy in yeast. Curr. Opinion Cell Biol. 21, (4), 522-530

  • Millen, J. I., Krick, R., Prick, T., Thumm, M., Goldfarb, D. S. (2009), Measuring piecemeal microautophagy of the nucleus in Saccharomyces cerevisiae. Autophagy 5, 75-81

2008

  • Prick, T., and M. Thumm. (2008), Measuring macroautophagy in S. cerevisiae: Autophagic body accumulation and total protein turnover. Methods in Enzymology 451, 57-66

  • Klionsky, D. J., et al. (2008), Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 4, 151-75

  • Santt, O., Pfirrmann, T., Braun, B., Juretschke, J., Kimmig, P., Scheel, H., Hofmann, K., Thumm, M. and Wolf, D. H. (2008), The Yeast GID Complex, a Novel Ubiquitin Ligase (E3) Involved in the Regulation of Carbohydrate Metabolism. Mol. Biol. Cell 19 (8), 3323-33

  • R. Krick*, Y. Muehe*, T. Prick*, S. Bremer, P. Schlotterhose, E.-L. Eskelinen, J. Millen, D. S. Goldfarb and M. Thumm (2008), Piecemeal microautophagy of the nucleus requires the core macroautophagy genes. Mol. Biol. Cell (19), 4492-4505

  • R. Krick, S. Henke, J. Tolstrup and M. Thumm (2008), Dissecting the localization and function of Atg18, Atg21 and Ygr223c. Autophagy 4(7) , 896-905

2006

  • Tanja Prick, Michael Thumm, Karl Köhrer, Dieter Häussinger and Stephan vom Dahl (2006), Osmosensitivity of autophagy in yeast is mediated by Hog1. Biochem. J. 394(1), 153-161

  • Tanja Prick, Michael Thumm, Dieter Häussinger and Stephan vom Dahl (2006), Deletion of HOG1 leads to osmosensitivity in starvation-induced, but not rapamycin-dependent Atg8 degradation and proteolysis: Further evidence for different regulatory mechanisms in yeast autophagy. Autophagy 2, 241-243

  • Roswitha Krick, Jörn Tolstrup, Anika Appelles, Sandra Henke and Michael Thumm (2006), The relevance of the phosphatidylinositolphosphat-binding motif FRRGT of Atg18 and Atg21 for the Cvt pathway and autophagy. FEBS Lett. 580, 4632-4638

2005

  • Khuyen Meiling-Wesse, Ulrike D. Epple, Henning Barth, Anika Appelles, Christiane Voss, Eeva-Liisa Eskelinen, and Michael Thumm (2005), Trs85 (Gsg1), a component of the TRAPP complexes is required for the organization of the preautophagosomal structure during selective autophagy via the Cvt pathway. J. Biol. Chem. 280, 33669-33678

2004

  • Khuyen Meiling-Wesse, Fotini Bratsika and Michael Thumm (2004), ATG23, a novel gene required for maturation of proaminopeptidase I, but not for autophagy. FEMS Yeast Research 4, 459-465

  • Jens Fricke, Christiane Voss, Michael Thumm and Gregor Meyers (2004), Processing of a pestivirus protein by a cellular protease specific for light chain 3 (LC3) of microtubule-associated proteins. J. Virology 78, 5900-5912

  • Tijs Ketelaar, Christiane Voss, Simon A. Dimmock, Michael Thumm, Patrick J. Hussey (2004), Arabidopsis homologues of the autophagy protein Atg8 are a novel family of microtubule binding proteins. FEBS Lett. 567, 302-306

  • Khuyen Meiling-Wesse, Henning Barth, Christiane Voss, Eeva-Liisa Eskelinen, Ulrike D. Epple and Michael Thumm (2004), Atg21 is required for effective recruitment of Atg8 to the preautophagosomal structure during the Cvt pathway. J. Biol. Chem. 279, 37741-37750

2003

  • U.D. Epple, E.-L. Eskelinen and M. Thumm (2003), Intravacuolar membrane lysis in Saccharomyces cerevisae: Does vacuolar targeting of Cvt17/Aut5p affect its function?. J.Biol.Chem. 278, 7810-7821

  • Jochen Regelmann, Thomas Schüle, Frank S. Josupeit, J. Horak, M. Rose, Karl-Dieter Entian, Michael Thumm and Dieter H. Wolf (2003), Catabolite degradation of fructose-1,6-bisphosphatase in the yeast Saccharomyces cerevisiae: A genome-wide screen identifies eight novel GID genes and indicates the existence of two degradation pathways. Mol. Biol. Cell 14, 1652-63