Publications as independent group leader (2014-)

 

7. Matea Perić, Anita Lovrić, Ana Šarić, Marina Musa, Peter Bou Dib, Marina Rudan, Andrea Nikolić, Sandra Sobočanec, Ana-Matea Mikecin, Sven Dennerlein, Ira Milošević, Kristian Vlahoviček, Nuno Raimundo, Anita Kriško (2017). TORC1-mediated sensing of chaperone activity alters glucose metabolism and extends lifespan. Aging Cell, 16: 994-1005

 

6. Cátia V. Diogo, King Faisal Yambire, Lorena Fernández Mosquera, Tiago Branco Fonseca, Nuno Raimundo* (2017). Mitochondrial adventures in the organelle society. Biochemical and Biophysical Research Communications. S0006-291X(17)30806-9. [invited review article, special issue on mitochondrial dynamics] *corresponding author

 

5. Lorena Fernández-Mosquera, Cátia V. Diogo, King Faisal Yambire, Gabriela L. Santos, Marta Luna Sánchez, Paule Bénit, Pierre Rustin, Luis Carlos Lopez, Ira Milosevic, Nuno Raimundo* (2016)

Acute and chronic mitochondrial respiratory chain deficiency differentially regulate lysosomal biogenesis. Scientific Reports, 7: 45076 *corresponding author

 

4. John D. Murdoch JD, Christine M. Rostosky, Sindhuja Gowrisankaran, Aman S. Arora, Sandra F. Soukup, Ramon Vidal, Vincenzo Capece, Syona Freytag, Andre Fischer, Patrick Verstreken, Stefan Bonn, Nuno Raimundo*, Ira Milosevic* (2016). Endophilin-A Deficiency Induces the Foxo3a-Fbxo32 Network in the Brain and Causes Dysregulation of Autophagy and the Ubiquitin-Proteasome System. Cell Reports, 17: 1071-1086 *corresponding authors

 

3. Nuno Raimundo*, Lorena Fernandez-Mosquera, King Faisal Yambire, Cátia V. Diogo (2016). Mechanisms of communication between mitochondria and lysosomes. International Journal of Biochemistry and Cell Biology, 79: 345-349 *corresponding author [invited review article]

 

2. Matea Perić, Peter Bou Dib, Anita Vidović, Marina Musa, Marina Rudan, Andrea Nikolić, Ana Šarić, Sandra Sobočanec, Željka Mačak, Nuno Raimundo, Anita Kriško (2016). TOR-mediated sensing of improved protein folding environment alters glucose metabolism and extends lifespan. Scientific Reports, 6: 28751

 

1. Nuno Raimundo (2014). Mitochondrial pathology: stress signals from the energy factory. Trends in Molecular Medicine 20: 282-292 [review article]

Publications from postdoctoral period

5. Sharen E. McKay, W. Yan, Jessica Nouws, M.J. Thormann, Nuno  Raimundo, A. Khan, Joseph Santos-Sacchi, Lei Song, Gerald Shadel (2015), Auditory Pathology in a Transgenic mtTFB1 Mouse Model of Mitochondrial Deafness. American Journal of Pathology 185: 3132-3140

4. A. Phillip West, Michal C. Tal, Matthew Staron, Cristiana M. Pineda, Nuno Raimundo, William Khoury-Hanold, Donna A. MacDuff, Herbert W. Virgin, Susan M. Kaech, Akiko Iwasaki, and Gerald S. Shadel (2015), Mitochondrial DNA Dynamics Direct a Cell-Intrinsic Antiviral Signaling Program. Nature 520: 553-557

3. Elizabeth Schroeder, Nuno Raimundo, Gerald Shadel (2013). Epigenetic Silencing Mediates Mitochondria Stress-induced Longevity. Cell Metabolism 17: 954-964

2. Nuno Raimundo, Lei Song, Timothy E. Shutt, Sharen E. McKay, Justin Cotney, Min-Xin Guan, Thomas C. Gilliland, David Hohuan, Joseph Santos-Sacchi and Gerald S. Shadel (2012). Mitochondrial stress engages E2F1 apoptotic signaling to cause deafness. Cell 148: 716-726

1. Nuno Raimundo*, Bora E. Baysal, Gerald S. Shadel (2011). Revisiting the TCA cycle: signaling to tumor formation. Trends in Molecular Medicine 17: 641-649 *Corresponding author [review article]

 

Publications from graduate school and before

4. Henna Tyynismaa*, Christopher J. Carroll*, Nuno Raimundo, Sofia Ahola-Erkkilä, Tina Wenz, Heini Ruhanen, Kilian Guse, Akseli Hemminki, Katja E. Peltola-Mjøsund, Valtteri Tulkki, Matej Orešič, Carlos T. Moraes, Kirsi Pietiläinen, Iiris Hovatta, Anu Suomalainen (2010). Mitochondrial myopathy induces a starvation-like response. Human Molecular Genetics 19: 3948-3958 *equal contribution

3. Nuno Raimundo, Sakari Vanharanta, Lauri A. Aaltonen, Iiris Hovatta, Anu Suomalainen (2009). Fumarate hydratase deficiency predisposition to leiomyoma formation involves down-regulation of FOS-JUNB pathway. Oncogene 28: 1261-1273.

2. Nuno Raimundo, Jouni Ahtinen, Ksenija Fumić, Ivo Barić, Anne M. Remes, Risto Renkonen, Risto Lapatto, Anu Suomalainen (2008). Fumarate hydratase deficiency is associated with reduced cell redox state. Biochimica et Biophysica Acta - Molecular Basis of Disease 1782: 287-294.

1. Maria P. Guarino, Ricardo A. Afonso, Nuno Raimundo, João F. Raposo, M. Paula Macedo (2003), Hepatic glutathione and nitric oxide are critical for hepatic insulin sensitizing substance (HISS) action. American Journal of Physiology Gastrointest Liver Physiol. 284: G588-G594.

 

Previews/comments

1. Nuno Raimundo, Gerald S. Shadel (2009), A “Radical” Mitochondrial View of Autophagyrelated Pathology. Aging 1: 354:356

 

2014

  • Raimundo N (2014), Mitochondrial pathology - stress signals from the energy factory. Trends in Molecular Medicine doi:10.1016/j.molmed.2014.01.005

2013

  • Schroeder EA, Raimundo N, Shadel GS (2013), Epigenetic silencing mediates mitochondria stress-induced longevity. Cell Metab 17, 954-964

2012

  • Raimundo N, Song L, Shutt TE, McKay SE, Cotney J, Guan MX, Gilliland TC, Hohuan D, Santos-Sacchi J, Shadel GS (2012), Mitochondrial stress engages E2F1 apoptotic signaling to cause deafness. Cell 148, 716-726

2011

  • Raimundo N, Baysal BE, Shadel GS (2011), Revisiting the TCA cycle: signaling to tumor formation. Trends Mol Med 17, 641-649

2010

  • Tyynismaa H, Carroll CJ, Raimundo N, Ahola-Erkkilä S, Wenz T, Ruhanen H, Guse K, Hemminki A, Peltola-Mjøsund KE, Tulkki V, Oresic M, Moraes CT, Pietiläinen K, Hovatta I, Suomalainen A (2010), Mitochondrial myopathy induces a starvation-like response. Hum Mol Genet 19, 3948-3958

2009

  • Raimundo N, Vanharanta S, Aaltonen LA, Hovatta I, Suomalainen A (2009), Downregulation of SRF-FOS-JUNB pathway in fumarate hydratase deficiency and in uterine leiomyomas.. Oncogene 28, 1261-1273

  • Raimundo N, Shadel GS (2009), A "radical" mitochondrial view of autophagy-related pathology.. Aging 1, 354-356

2008

  • Raimundo N, Ahtinen J, Fumić K, Barić I, Remes AM, Renkonen R, Lapatto R, Suomalainen A (2008), Differential metabolic consequences of fumarate hydratase and respiratory chain defects. Biochim Biophys Acta 1782, 287-294

2003

Maria P. Guarino, Ricardo A. Afonso, Nuno Raimundo, João F. Raposo, M. Paula Macedo (2003), Hepatic glutathione and nitric oxide are critical for hepatic insulin sensitizing substance (HISS) action. American Journal of Physiology Gastrointest Liver Physiol. 284, G588-G594