since 2003


Original publications


  • Lorenzi, I., Oeljeklaus, S., Aich, A., Ronsör, C., Callegari, S., Dudek, J., Warscheid, B., Dennerlein, S., and Rehling, P. (2017) The mitochondrial TMEM177 associates with COX20 during COX2 biogenesis. Biochim. Biophys. Acta [Epub ahead of print]

  • Levchenko M., Lorenzi I., Dudek J. (2016) The Degradation Pathway of the Mitophagy Receptor Atg32 Is Re-Routed by a Posttranslational Modification. PLoS One 11, 1-17.

  • Callegari S., Oeljeklaus S., Warscheid B., Dennerlein S., Thumm M., Rehling P., Dudek J. (2016) Phospho-ubiquitin-PARK2 complex as a marker for mitophagy defects. Autophagy 15, 1-11.

  • Guentsch A., Beneke A., Swain L., Farhat K., Nagarajan S., Wielockx B., Raithatha K., Dudek J., Rehling P., Zieseniss A., Jatho A., Chong M., Santos C.X., Shah A.M., Katschinski D.M. (2016) PHD2 Is a Regulator for Glycolytic Reprogramming in Macrophages. Mol. Cell Biol. 37, 1-17.

  • Callegari S., Richter F., Chojnacka K., Jans D.C., Lorenzi I., Pacheu-Grau D., Jakobs S., Lenz C., Urlaub H., Dudek J., Chacinska A., Rehling P. (2016) TIM29 is a subunit of the human carrier translocase required for protein transport. FEBS Lett. 590, 4147-4158.

  • Review: Dudek, J., Maack, C., (2017) Barth Syndrome Cardiomyopathy. Cardiovascular Research (invited article, accepted for publication).

  • Dudek, J., Cheng, I.F., Chowdhury, A., Wozny, K.,  Balleininger, M., Reinhold, R., Grunau, S., Callegari, S., Toischer, K., Wanders, R.A.J., Hasenfuß, G., Brügger, B.,  Guan, K., Rehling, P. (2015) Cardiac-specific Succinate Dehydrogenase Deficiency in Barth Syndrome EMBO Mol. Med. 8, 139-54

  • Pacheu-Grau, D., Bareth, B., Dudek, J., Juris, L., Vögtle, F.-N., Wissel, M., Leary, S., Dennerlein, S., Rehling, P., Deckers, M. (2015) Cooperation between COA6 and SCO2 in COX2 maturation during cytochrome c oxidase assembly links two mitochondrial cardiomyopathies. Cell Metabolism 21, 823-833
  • Deckers, M., Balleininger, M., Vukotic, M., Roempler, K., Bareth, B., Juris, L., Dudek, J., (2014) Aim24 stabilizes respiratory chain supercomplexes and is required for efficient respiration. FEBS letters. 588, 2985-2992
  • Welter, E., Montino, M., Reinhold, R., Schlotterhose, P., Krick, R., Dudek, J., Rehling, P., Thumm, M. (2013) Uth1 is a mitochondrial inner membrane protein dispensable for post-log-phase and rapamycin-induced mitophagy. FEBS J. 280, 4970-4982

  • Dudek*, J., Cheng* I. F., Balleininger, M., Vaz, F. M., Streckfuss-Bömeke, K., Hübscher, D., Vukotic, M., Wanders, R. J., Rehling, P., Guan, K. (2013) Cardiolipin deficiency affects respiratory chain function and organization in an induced pluripotent stem cell model of Barth syndrome. Stem Cell Res. 11, 806-819
  • Reinhold, R., Krüger, V., Meinecke, M., Schulz, C., Schmidt, B., Grunau, S. D., Guiard B., Wiedemann, N., van der Laan, M., Wagner, R., Rehling, P., Dudek J. (2012) The channel-forming Sym1 protein is transported by the TIM23 complex in a presequence-independent manner. Mol Cell Biol., 32, 5009-5021
  • Van der Laan, M., Meinecke, M., Dudek, J., Hutu, D. P., Lind, M., Perschil, I., Guiard, B., Wagner, R., Pfanner, N., Rehling, P. (2007) Motor-free mitochondrial presequence translocase drives membrane integration of preproteins. Nat. Cell Biol., 10, 1152-1159
  • Chacinska, A., Lind, M., Frazier, A. E., Dudek, J., Meisinger, C., Geissler, A., Sickmann, A., Meyer, H. E., Truscott, K. N., Guiard, B., Pfanner, N., Rehling, P. (2005) Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17. Cell, 120, 817-829
  • Li*, Y., Dudek*, J., Guiard, B., Pfanner, N., Rehling, P., Voos, W. (2004) The presequence translocase-associated protein import motor of mitochondria. Pam16 functions in an antagonistic manner to Pam18. J. Biol. Chem., 279, 38047-38054

  • Frazier*, A. E., Dudek*, J., Guiard, B., Voos, W., Li, Y., Lind, M., Meisinger, C., Geissler, A., Sickmann, A., Meyer, H. E., Bilanchone, V., Cumsky, M. G., Truscott, K. N., Pfanner, N., Rehling, P. (2004) Pam16 has an essential role in the mitochondrial protein import motor. Nat. Struct. Mol. Biol., 11, 226-233
  • Truscott, K. N., Voos, W., Frazier, A. E., Lind, M., Li, Y., Geissler, A., Dudek, J., Müller, H., Sickmann, A., Meyer, H. E., Meisinger, C., Guiard, B., Rehling, P., Pfanner, N. (2003) A J-protein is an essential subunit of the presequence translocase-associated protein import motor of mitochondria. J. Cell Biol., 163, 707-713.

     (* Authors with equal contributions to the work)



  • Dudek, J., Rehling, P., van der Laan, M. (2013) Mitochondrial protein import: common principles and physiological networks. Biochim Biophys Acta., 1833, 274-285
  • Dudek, J., Guiard, B., Rehling, P. (2007) The Role of TIM23/Hsp70 in Mitochondrial Protein Import. Molecular Machines Involved in Protein Transport Across Cellular Membranes. The Enzymes, Vol. 25, Academic Press/Elsevier