{"id":4591,"date":"2021-07-14T18:33:27","date_gmt":"2021-07-14T16:33:27","guid":{"rendered":"https:\/\/biochemie2.uni-goettingen.de\/?page_id=4591"},"modified":"2025-10-28T18:06:19","modified_gmt":"2025-10-28T17:06:19","slug":"mitochondrial-protein-biogenesis-publications","status":"publish","type":"page","link":"https:\/\/biochemie.uni-goettingen.de\/index.php\/mitochondrial-protein-biogenesis-publications\/","title":{"rendered":"Mitochondrial protein biogenesis (Publications)"},"content":{"rendered":"

Publications (since 2003)<\/b><\/h3>\n

2025<\/b>
\nReshetniak S, Bogaciu CA, Bonn S, Brose N, Cooper BH, D’Este E, Fauth M, Fern\u00e1ndez-Busnadiego R, Fiosins M, Fischer A, Georgiev SV, Jakobs S, Klumpp S, K\u00f6ster S, Lange F, Lipstein N, Macarr\u00f3n-Palacios V, Milovanovic D, Moser T, M\u00fcller M, Opazo F, Outeiro TF, Pape C, Priesemann V, Rehling P, Salditt T, Schl\u00fcter O, Simeth N, Steinem C, Tchumatchenko T, Tetzlaff C, Tirard M, Urlaub H, Wichmann C, Wolf F, Rizzoli SO. (2025) The synaptic vesicle cluster as a controller of pre- and postsynaptic structure and function. J Physiol.<\/b> 2025 Oct;603(20):5935-5964.<\/a><\/p>\n

Dahal D, Cruz-Zargoza LD, Rehling P. (2025) Manipulating mitochondrial gene expression. Biol Chem.<\/b> 2025 Sep 15.<\/a><\/p>\n

Stoldt S, Maass F, Weber M, Dennerlein S, Ilgen P, G\u00e4rtner J, Canfes A, Schweighofer SV, Jans DC, Rehling P, Jakobs S. (2025) Super-resolution microscopy of mitochondrial mRNAs. Nat Commun.<\/b> 2025 Jul 10;16(1):6391.<\/a><\/p>\n

Jain N, Chacinska A, Rehling P. (2025) Understanding mitochondrial protein import: a revised model of the presequence translocase. Trends Biochem Sci.<\/b> 2025 Jul;50(7):585-595.<\/a><\/p>\n

Boshnakovska A, Pronto JR, Gall T, Aich A, Prochazka J, Nichtova Z, Sedlacek R, Sobitov I, Ainatzi S, Lenz C, Katschinski DM, Urlaub H, Voigt N, Rehling P, Kremer LS. (2025) SMIM20 promotes complex IV biogenesis and Ca2+ signaling in mice heart. Cell Rep.<\/b> 2025 Jun 24;44(6):115723.<\/a><\/p>\n

Cruz-Zaragoza LD, Dahal D, Koschel M, Boshnakovska A, Zheenbekova A, Yilmaz M, Morgenstern M, Dohrke JN, Bender J, Valpadashi A, Henningfeld KA, Oeljeklaus S, Kremer LS, Breuer M, Urbach O, Dennerlein S, Lidschreiber M, Jakobs S, Warscheid B, Rehling P. (2025) Silencing mitochondrial gene expression in living cells. Science.<\/b> 2025 May 22;389(6759):eadr3498.<\/a><\/p>\n

Boshnakovska A, Pronto JR, Gall T, Aich A, Prochazka J, Nichtova Z, Sedlacek R, Sobitov I, Ainatzi S, Lenz C, Katschinski DM, Urlaub H, Voigt N, Rehling P, Kremer LS (2025) SMIM20 promotes complex IV biogenesis and Ca2+ signaling in mice heart. Cell Rep.<\/b> 2025 May 20;44(6):115723.<\/a><\/p>\n

Fenech EJ, Kupervaser M, Boshnakovska A, Ravid S, Castro IG, Asraf Y, Callegari S, Lenz C, Urlaub H, Rehling P, Schuldiner M (2025) Profiling the LAM Family of Contact Site Tethers Provides Insights into Their Regulation and Function. Contact (Thousand Oaks).<\/b> 2025 Apr 17;8:25152564251321770. eCollection 2025 Jan-Dec.<\/a><\/p>\n

Heinrichs M, Finke AF, Aibara S, Krempler A, Boshnakovska A, Rehling P, Hillen HS, Richter-Dennerlein R (2025) Coupling of ribosome biogenesis and translation initiation in human mitochondria. Nat Commun.<\/b> 2025 Apr 17;16(1):3641.<\/a><\/p>\n

Maurer W, Zieseniss A, Priya VP, Chen Y, Bauer L, Hillemann A, Rehling P, Nanadikar MS, de Z\u00e9licourt D, Kurtcuoglu V, Katschinski DM (2025) D-amino acid oxidase as a chemogenetic tool for spatiotemporally controlled hydrogen peroxide production: The oxygen connection. Br J Pharmacol.<\/b> 2025 Apr 15.<\/a><\/p>\n

Jain N, Chacinska A, Rehling P (2025) Understanding mitochondrial protein import: a revised model of the presequence translocase. Trends Biochem Sci.<\/b> 2025 Mar 27:S0968-0004(25)00050-7.<\/a><\/p>\n

Valenti R, David Y, Edilbi D, Dubreuil B, Boshnakovska A, Asraf Y, Salame TM, Sass E, Rehling P, Schuldiner M (2025) A proteome-wide yeast degron collection for the dynamic study of protein function. J Cell Biol.<\/b> 2025 Feb 3;224(2):e202409050. Epub 2024 Dec 18.<\/a><\/p>\n

Oborsk\u00e1-Oplov\u00e1 M, Geiger AG, Michel E, Klingauf-Nerurkar P, Dennerlein S, Bykov YS, Amodeo S, Schneider A, Schuldiner M, Rehling P, Panse VG (2025) An avoidance segment resolves a lethal nuclear-mitochondrial targeting conflict during ribosome assembly. Nat Cell Biol.<\/b> 2025 Feb;27(2):336-346. Epub 2025 Jan 31.<\/a><\/p>\n

Yousefi R, Cruz-Zaragoza LD, Valpadashi A, Hansohn C, Dahal D, Richter-Dennerlein R, Rizzoli S, Urlaub H, Rehling P, Pacheu-Grau D (2025) A microscopy-based screen identifies cellular kinases modulating mitochondrial translation. Cell Rep.<\/b> 2025 Jan 28;44(1):115143. Epub 2024 Dec 31.<\/a><\/p>\n

2024<\/b>
\nShumanska M, Lodygin D, Gibhardt CS, Ickes C, Stejerean-Todoran I, Krause LCM, Pahl K, Jacobs LJHC, Paluschkiwitz A, Liu S, Boshnakovska A, Voigt N, Legler TJ, Haubrock M, Mitkovski M, Poschmann G, Rehling P, Dennerlein S, Riemer J, Fl\u00fcgel A, Bogeski I (2024) Mitochondrial calcium uniporter complex controls T-cell-mediated immune responses. EMBO Rep<\/b> 2025 Jan;26(2):407-442. Epub 2024 Dec 2.<\/a><\/p>\n

Jain N, Gomkale R, Rehling P (2024) TOM-TIM23 supercomplex formation. Methods Enzymol<\/b> 707, 3-22.<\/a><\/p>\n

Foo B, Amedei H, Kaur S, Jaawan S, Boshnakovska A, Gall T, de Boer RA, Sillj\u00e9 HHW, Urlaub H, Rehling P, Lenz C, Lehnart SE (2024) Unbiased complexome profiling and global proteomics analysis reveals mitochondrial impairment and potential changes at the intercalated disk in presymptomatic R14\u0394\/+ mice hearts. PLoS One<\/b> 19, e0311203.<\/a><\/p>\n

Reshetniak S, Bogaciu CA, Bonn S, Brose N, Cooper BH, D’Este E, Fauth M, Fern\u00e1ndez-Busnadiego R, Fiosins M, Fischer A, Georgiev SV, Jakobs S, Klumpp S, K\u00f6ster S, Lange F, Lipstein N, Macarr\u00f3n-Palacios V, Milovanovic D, Moser T, M\u00fcller M, Opazo F, Outeiro TF, Pape C, Priesemann V, Rehling P, Salditt T, Schl\u00fcter O, Simeth N, Steinem C, Tchumatchenko T, Tetzlaff C, Tirard M, Urlaub H, Wichmann C, Wolf F, Rizzoli SO (2024) The synaptic vesicle cluster as a controller of pre- and postsynaptic structure and function. J Physiol<\/b> 2024 Oct 5.<\/a><\/p>\n

Aich A, Boshnakovska A, Witte S, Gall T, Unthan-Fechner K, Yousefi R, Chowdhury A, Dahal D, Methi A, Kaufmann S, Silbern I, Prochazka J, Nichtova Z, Palkova M, Raishbrook M, Koubkova G, Sedlacek R, Tr\u00f6der SE, Zevnik B, Riedel D, Michanski S, M\u00f6bius W, Str\u00f6bel P, L\u00fcchtenborg C, Giavalisco P, Urlaub H, Fischer A, Br\u00fcgger B, Jakobs S, Rehling P (2024) Defective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in mouse liver. Nat Commun<\/b> 15, 6914.<\/a><\/p>\n

Schneider C, Hilbert J, Genevaux F, H\u00f6fer S, Krau\u00df L, Schicktanz F, Contreras CT, Jansari S, Papargyriou A, Richter T, Alfayomy AM, Falcomat\u00e0 C, Schneeweis C, Orben F, \u00d6llinger R, Wegwitz F, Boshnakovska A, Rehling P, M\u00fcller D, Str\u00f6bel P, Ellenrieder V, Conradi L, Hessmann E, Ghadimi M, Grade M, Wirth M, Steiger K, Rad R, Kuster B, Sippl W, Reichert M, Saur D, Schneider G (2024) A Novel AMPK Inhibitor Sensitizes Pancreatic Cancer Cells to Ferroptosis Induction. Adv Sci (Weinh)<\/b> , e2307695.<\/a><\/p>\n

Kremer LS, Rehling P (2024) Coordinating mitochondrial translation with assembly of the OXPHOS complexes. Hum Mol Genet<\/b> 33, R47-R52.<\/a><\/p>\n

Zung N, Aravindan N, Boshnakovska A, Valenti R, Preminger N, Jonas F, Yaakov G, Willoughby MM, Homberg B, Keller J, Kupervaser M, Dezorella N, Dadosh T, Wolf SG, Itkin M, Malitsky S, Brandis A, Barkai N, Fern\u00e1ndez-Busnadiego R, Reddi AR, Rehling P, Rapaport D, Schuldiner M (2024) The molecular mechanism of on-demand sterol biosynthesis at organelle contact sites. bioRxiv <\/b>[Preprint]. 2024 May 12:2024.05.09.593285.<\/a><\/p>\n

Garg P, W\u00fcrtz F, Hobbie F, Buttgereit K, Aich A, Leite K, Rehling P, K\u00fcgler S, B\u00e4hr M (2024) Human serum-derived \u03b1-synuclein auto-antibodies mediate NMDA receptor-dependent degeneration of CNS neurons. J Neuroinflammation<\/b> 21, 62.<\/a><\/p>\n

Prokakis E, Bamahmoud H, Jansari S, Fritsche L, Dietz A, Boshnakovska A, Rehling P, Johnsen SA, Gallwas J, Wegwitz F (2024) USP22 supports the aggressive behavior of basal-like breast cancer by stimulating cellular respiration. Cell Commun Signal<\/b> 22, 120.<\/a><\/p>\n

Stephan T, Stoldt S, Barbot M, Carney TD, Lange F, Bates M, Bou Dib P, Inamdar K, Shcherbata HR, Meinecke M, Riedel D, Dennerlein S, Rehling P, Jakobs S (2024) Drosophila MIC10b can polymerize into cristae-shaping filaments. Life Sci Alliance<\/b> 7(4):e202302177.<\/a><\/p>\n

Poerschke S, Oeljeklaus S, Cruz-Zaragoza LD, Schenzielorz A, Dahal D, Hillen HS, Das H, Kremer LS, Valpadashi A, Breuer M, Sattmann J, Richter-Dennerlein R, Warscheid B, Dennerlein S, Rehling P Identification of TMEM126A as OXA1L-interacting protein reveals cotranslational quality control in mitochondria. Mol Cell 84(2):345-358.e5.<\/a><\/p>\n

2023
\n<\/b>Kutschka I, Bertero E, Wasmus C, Xiao K, Yang L, Chen X, Oshima Y, Fischer M, Erk M, Arslan B, Alhasan L, Grosser D, Ermer KJ, Nickel A, Kohlhaas M, Eberl H, Rebs S, Streckfuss-B\u00f6meke K, Schmitz W, Rehling P, Thum T, Higuchi T, Rabinowitz J, Maack C, Dudek J (2023) Activation of the integrated stress response rewires cardiac metabolism in Barth syndrome. Basic Res Cardiol<\/b> 118, 47.<\/a><\/p>\n

Stewart H, Lu Y, O’Keefe S, Valpadashi A, Cruz-Zaragoza LD, Michel HA, Nguyen SK, Carnell GW, Lukhovitskaya N, Milligan R, Adewusi Y, Jungreis I, Lulla V, Matthews DA, High S, Rehling P, Emmott E, Heeney JL, Davidson AD, Edgar JR, Smith GL, Firth AE (2023) The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity. iScience<\/b> 26, 108080.<\/a><\/p>\n

Prokakis E, Jansari S, Boshnakovska A, Wiese M, Kusch K, Kramm C, Dullin C, Rehling P, Glatzel M, Pantel K, Wikman H, Johnsen SA, Gallwas J, Wegwitz F (2023) RNF40 epigenetically modulates glycolysis to support the aggressiveness of basal-like breast cancer. Cell Death Dis<\/b> 14, 641.<\/a><\/p>\n

Chowdhury A, Boshnakovska A, Aich A, Methi A, Vergel Leon AM, Silbern I, L\u00fcchtenborg C, Cyganek L, Prochazka J, Sedlacek R, Lindovsky J, Wachs D, Nichtova Z, Zudova D, Koubkova G, Fischer A, Urlaub H, Br\u00fcgger B, Katschinski DM, Dudek J, Rehling P (2023) Metabolic switch from fatty acid oxidation to glycolysis in knock-in mouse model of Barth syndrome. EMBO Mol Med<\/b> , e17399.<\/a><\/p>\n

Dennerlein S, Rehling P, Richter-Dennerlein R (2023) Cytochrome c oxidase biogenesis – from translation to early assembly of the core subunit COX1. FEBS Lett<\/b> 597(12):1569-1578.<\/a><\/p>\n

Makki A, Rehling P (2023) Protein transport along the presequence pathway. Biol Chem<\/b> 404(8-9):807-812.<\/a><\/p>\n

Nanadikar MS, Vergel Leon AM, Guo J, van Belle GJ, Jatho A, Philip ES, Brandner AF, B\u00f6ckmann RA, Shi R, Zieseniss A, Siemssen CM, Dettmer K, Brodesser S, Schmidtendorf M, Lee J, Wu H, Furdui CM, Brandenburg S, Burgoyne JR, Bogeski I, Riemer J, Chowdhury A, Rehling P, Bruegmann T, Belousov VV, Katschinski DM (2023) IDH3\u03b3 functions as a redox switch regulating mitochondrial energy metabolism and contractility in the heart. Nat Commun<\/b> 14, 2123.<\/a><\/p>\n

Jain N, Gomkale R, Bernhard O, Rehling P, Cruz-Zaragoza LD (2023) A quantitative fluorescence-based approach to study mitochondrial protein import. EMBO Rep<\/b> , e55760.<\/a><\/p>\n

Homberg B, Rehling P, Cruz-Zaragoza LD (2023) The multifaceted mitochondrial OXA insertase. Trends Cell Biol<\/b> 33(9):765-772.<\/a><\/p>\n

Witte S, Boshnakovska A, \u00d6zdemir M, Chowdhury A, Rehling P, Aich A (2023) Defective COX1 expression in aging mice liver. Biol Open<\/b> 12(3):bio059844.<\/a><\/p>\n

2022<\/b>
\nStejerean-Todoran I, Zimmermann K, Gibhardt CS, Vultur A, Ickes C, Shannan B, Bonilla Del Rio Z, W\u00f6lling A, Cappello S, Sung HM, Shumanska M, Zhang X, Nanadikar M, Latif MU, Wittek A, Lange F, Waters A, Brafford P, Wilting J, Urlaub H, Katschinski DM, Rehling P, Lenz C, Jakobs S, Ellenrieder V, Roesch A, Sch\u00f6n MP, Herlyn M, Stanisz H, Bogeski I (2022) MCU controls melanoma progression through a redox-controlled phenotype switch. EMBO Rep<\/b> , e54746.<\/a><\/p>\n

Fan Y, Murgia M, Linder MI, Mizoguchi Y, Wang C, \u0141yszkiewicz M, Zi\u0229tara N, Liu Y, Frenz S, Sciuccati G, Partida-Gaytan A, Alizadeh Z, Rezaei N, Rehling P, Dennerlein S, Mann M, Klein C (2022) HAX1-dependent control of mitochondrial proteostasis governs neutrophil granulocyte differentiation. J Clin Invest<\/b> 132(9):e153153.<\/a><\/p>\n

Chojnacka KJ, Elancheliyan P, Mussulini BHM, Mohanraj K, Callegari S, Gosk A, Banach T, G\u00f3ral T, Szczepanowska K, Rehling P, Serwa RA, Chaci\u0144ska A (2022) Ovarian carcinoma immunoreactive antigen-like protein 2 (OCIAD2) is a novel complex III specific assembly factor in mitochondria. Mol Biol Cell<\/b> , mbcE21030143.<\/a><\/p>\n

2021<\/b>
\nDennerlein S, Poerschke S, Oeljeklaus S, Wang C, Richter-Dennerlein R, Sattmann J, Bauermeister D, Hanitsch E, Stoldt S, Langer T, Jakobs S, Warscheid B, Rehling P (2021) Defining the interactome of the human mitochondrial ribosome identifies SMIM4 and TMEM223 as respiratory chain assembly factors. Elife<\/b> 10:e68213.<\/a><\/p>\n

Kettwig M, Ternka K, Wendland K, Kr\u00fcger DM, Zampar S, Schob C, Franz J, Aich A, Winkler A, Sakib MS, Kaurani L, Epple R, Werner HB, Hakroush S, Kitz J, Prinz M, Bartok E, Hartmann G, Schr\u00f6der S, Rehling P, Henneke M, Boretius S, Alia A, Wirths O, Fischer A, Stadelmann C, Nessler S, G\u00e4rtner J (2021) Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy. Nat Commun<\/b> 12, 6530.<\/a><\/p>\n

Cruz-Zaragoza LD, Dennerlein S, Linden A, Yousefi R, Lavdovskaia E, Aich A, Falk RR, Gomkale R, Sch\u00f6ndorf T, Bohnsack MT, Richter-Dennerlein R, Urlaub H, Rehling P (2021) An in vitro system to silence mitochondrial gene expression. Cell<\/b> 184, 5824-5837.e15.<\/a><\/p>\n

Bertero E, Nickel A, Kohlhaas M, Hohl M, Sequeira V, Brune C, Schwemmlein J, Abe\u00dfer M, Schuh K, Kutschka I, Carlein C, M\u00fcnker K, Atighetchi S, M\u00fcller A, Kazakov A, Kappl R, von der Malsburg K, van der Laan M, Schiuma AF, B\u00f6hm M, Laufs U, Hoth M, Rehling P, Kuhn M, Dudek J, von der Malsburg A, Prates Roma L, Maack C (2021) Loss of Mitochondrial Ca2+<\/sup> Uniporter Limits Inotropic Reserve and Provides Trigger and Substrate for Arrhythmias in Barth Syndrome Cardiomyopathy. Circulation<\/b> 144, 1694-1713.<\/a><\/p>\n

Gomkale R, Linden A, Neumann P, Schendzielorz AB, Stoldt S, Dybkov O, Kilisch M, Schulz C, Cruz-Zaragoza LD, Schwappach B, Ficner R, Jakobs S, Urlaub H, Rehling P (2021) Mapping protein interactions in the active TOM-TIM23 supercomplex. Nat Commun<\/b> 12, 5715.<\/a><\/p>\n

Cappello S, Sung HM, Ickes C, Gibhardt CS, Vultur A, Bhat H, Hu Z, Brafford P, Denger A, Stejerean-Todoran I, K\u00f6hn RM, Lorenz V, K\u00fcnzel N, Salinas G, Stanisz H, Legler T, Rehling P, Sch\u00f6n MP, Lang KS, Helms V, Herlyn M, Hoth M, Kummerow C, Bogeski I (2021) Protein Signatures of NK Cell-Mediated Melanoma Killing Predict Response to Immunotherapies. Cancer Res<\/b> 81, 5540-5554.<\/a><\/p>\n

Chacinska A, Rehling P (2021) Molecular bases of mitochondrial disorders. FEBS Lett<\/b> 595, 973-975.<\/a><\/p>\n

Yousefi R, Fornasiero EF, Cyganek L, Montoya J, Jakobs S, Rizzoli SO, Rehling P, Pacheu-Grau D (2021) Monitoring mitochondrial translation in living cells. EMBO Rep<\/b> 22, e51635.<\/a><\/p>\n

Reinert MC, Pacheu-Grau D, Catarino CB, Klopstock T, Ohlenbusch A, Schittkowski M, Wilichowski E, Rehling P, Brockmann K (2021) Sulthiame impairs mitochondrial function in vitro and may trigger onset of visual loss in Leber hereditary optic neuropathy. Orphanet J Rare Dis<\/b> 16, 64.<\/a><\/p>\n

Peper J, Kownatzki-Danger D, Weninger G, Seibertz F, Pronto JRD, Sutanto H, Pacheu-Grau D, Hindmarsh R, Brandenburg S, Kohl T, Hasenfuss G, Gotthardt M, Rog-Zielinska EA, Wollnik B, Rehling P, Urlaub H, Wegener J, Heijman J, Voigt N, Cyganek L, Lenz C, Lehnart SE (2021) Caveolin3 Stabilizes McT1-Mediated Lactate\/Proton Transport in Cardiomyocytes. Circ Res<\/b> 128, e102-e120.<\/a><\/p>\n

Valpadashi A, Callegari S, Linden A, Neumann P, Ficner R, Urlaub H, Deckers M, Rehling P (2021) Defining the architecture of the human TIM22 complex by chemical crosslinking. FEBS Lett<\/b> 595, 157-168.<\/a><\/p>\n

2020<\/b>
\nStephan T, Br\u00fcser C, Deckers M, Steyer AM, Balzarotti F, Barbot M, Behr TS, Heim G, H\u00fcbner W, Ilgen P, Lange F, Pacheu-Grau D, Pape JK, Stoldt S, Huser T, Hell SW, M\u00f6bius W, Rehling P, Riedel D, Jakobs S (2020) MICOS assembly controls mitochondrial inner membrane remodeling and crista junction redistribution to mediate cristae formation. EMBO J<\/b> 39, e104105.<\/a><\/p>\n

Linden A, Deckers M, Parfentev I, Pflanz R, Homberg B, Neumann P, Ficner R, Rehling P, Urlaub H (2020) A Cross-linking Mass Spectrometry Approach Defines Protein Interactions in Yeast Mitochondria. Mol Cell Proteomics<\/b> 19, 1161-1178.<\/a><\/p>\n

Gomkale R, Cruz-Zaragoza LD, Suppanz I, Guiard B, Montoya J, Callegari S, Pacheu-Grau D, Warscheid B, Rehling P (2020) Defining the Substrate Spectrum of the TIM22 Complex Identifies Pyruvate Carrier Subunits as Unconventional Cargos. Curr Biol<\/b> 30, 1119-11127.e5.<\/a><\/p>\n

Callegari S, Cruz-Zaragoza LD, Rehling P (2020) From TOM to the TIM23 complex – handing over of a precursor. Biol Chem<\/b> 401, 709-721.<\/a><\/p>\n

Pacheu-Grau D, Wasilewski M, Oeljeklaus S, Gibhardt CS, Aich A, Chudenkova M, Dennerlein S, Deckers M, Bogeski I, Warscheid B, Chacinska A, Rehling P (2020) COA6 Facilitates Cytochrome c Oxidase Biogenesis as Thiol-reductase for Copper Metallochaperones in Mitochondria. J Mol Biol<\/b> 432, 2067-2079.<\/a><\/p>\n

Wang C, Richter-Dennerlein R, Pacheu-Grau D, Liu F, Zhu Y, Dennerlein S, Rehling P (2020) MITRAC15\/COA1 promotes mitochondrial translation in a ND2 ribosome-nascent chain complex. EMBO Rep<\/b> 21, e48833.<\/a><\/p>\n

2019<\/b>
\nZhang X, Gibhardt CS, Will T, Stanisz H, K\u00f6rbel C, Mitkovski M, Stejerean I, Cappello S, Pacheu-Grau D, Dudek J, Tahbaz N, Mina L, Simmen T, Laschke MW, Menger MD, Sch\u00f6n MP, Helms V, Niemeyer BA, Rehling P, Vultur A, Bogeski I (2019) Redox signals at the ER-mitochondria interface control melanoma progression. EMBO J<\/b> 38, e100871.<\/a><\/p>\n

Callegari S, Rehling P (2019) Guarding the gate for mitochondrial entry. Nature<\/b> 569, 635-637.<\/a><\/p>\n

Can K, Menzfeld C, Rinne L, Rehling P, K\u00fcgler S, Golubiani G, Dudek J, M\u00fcller M (2019) Neuronal Redox-Imbalance in Rett Syndrome Affects Mitochondria as Well as Cytosol, and Is Accompanied by Intensified Mitochondrial O 2<\/i><\/sub> Consumption and ROS Release. Front Physiol<\/b> 10, 479.<\/a><\/p>\n

Callegari S, M\u00fcller T, Schulz C, Lenz C, Jans DC, Wissel M, Opazo F, Rizzoli SO, Jakobs S, Urlaub H, Rehling P, Deckers M (2019) A MICOS-TIM22 Association Promotes Carrier Import into Human Mitochondria. J Mol Biol<\/b> 431, 2835-2851.<\/a><\/p>\n

Mohanraj K, Wasilewski M, Beninc\u00e1 C, Cysewski D, Poznanski J, Sakowska P, Bugajska Z, Deckers M, Dennerlein S, Fernandez-Vizarra E, Rehling P, Dadlez M, Zeviani M, Chacinska A (2019) Inhibition of proteasome rescues a pathogenic variant of respiratory chain assembly factor COA7. EMBO Mol Med<\/b> 11: e9561.<\/a><\/p>\n

Dudek J, Hartmann M, Rehling P (2019) The role of mitochondrial cardiolipin in heart function and its implication in cardiac disease. Biochim Biophys Acta Mol Basis Dis<\/b> 1865, 810-821.<\/a><\/p>\n

Nanadikar MS, Vergel Leon AM, Borowik S, Hillemann A, Zieseniss A, Belousov VV, Bogeski I, Rehling P, Dudek J, Katschinski DM (2019) O2<\/sub> affects mitochondrial functionality ex vivo. Redox Biol<\/b> 22, 101152.<\/a><\/p>\n

Antunes D, Chowdhury A, Aich A, Saladi S, Harpaz N, Stahl M, Schuldiner M, Herrmann JM, Rehling P, Rapaport D (2019) Overexpression of branched-chain amino acid aminotransferases rescues the growth defects of cells lacking the Barth syndrome-related gene TAZ1. J Mol Med (Berl)<\/b> 97, 269-279.<\/a><\/p>\n

Richter F, Dennerlein S, Nikolov M, Jans DC, Naumenko N, Aich A, MacVicar T, Linden A, Jakobs S, Urlaub H, Langer T, Rehling P (2019) ROMO1 is a constituent of the human presequence translocase required for YME1L protease import. J Cell Biol<\/b> 218, 598-614.<\/a><\/p>\n

2018<\/b>
\nSaal KA, Richter F, Rehling P, Rizzoli SO (2018) Combined Use of Unnatural Amino Acids Enables Dual-Color Super-Resolution Imaging of Proteins via Click Chemistry. ACS Nano<\/b> 12, 12247-12254.<\/a><\/p>\n

Pacheu-Grau D, Callegari S, Emperador S, Thompson K, Aich A, Topol SE, Spencer EG, McFarland R, Ruiz-Pesini E, Torkamani A, Taylor RW, Montoya J, Rehling P (2018) Mutations of the mitochondrial carrier translocase channel subunit TIM22 cause early-onset mitochondrial myopathy. Hum Mol Genet<\/b> 27, 4135-4144.<\/a><\/p>\n

Mandad S, Rahman RU, Centeno TP, Vidal RO, Wildhagen H, Rammner B, Keihani S, Opazo F, Urban I, Ischebeck T, Kirli K, Benito E, Fischer A, Yousefi RY, Dennerlein S, Rehling P, Feussner I, Urlaub H, Bonn S, Rizzoli SO, Fornasiero EF (2018) The codon sequences predict protein lifetimes and other parameters of the protein life cycle in the mouse brain. Sci Rep<\/b> 8, 16913.<\/a><\/p>\n

Chowdhury A, Aich A, Jain G, Wozny K, L\u00fcchtenborg C, Hartmann M, Bernhard O, Balleiniger M, Alfar EA, Zieseniss A, Toischer K, Guan K, Rizzoli SO, Br\u00fcgger B, Fischer A, Katschinski DM, Rehling P, Dudek J (2018) Defective Mitochondrial Cardiolipin Remodeling Dampens HIF-1\u03b1 Expression in Hypoxia. Cell Rep<\/b> 25, 561-570.e6.<\/a><\/p>\n

Fornasiero EF, Mandad S, Wildhagen H, Alevra M, Rammner B, Keihani S, Opazo F, Urban I, Ischebeck T, Sakib MS, Fard MK, Kirli K, Centeno TP, Vidal RO, Rahman RU, Benito E, Fischer A, Dennerlein S, Rehling P, Feussner I, Bonn S, Simons M, Urlaub H, Rizzoli SO (2018) Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions. Nat Commun<\/b> 9, 4230.<\/a><\/p>\n

Schendzielorz AB, Bragoszewski P, Naumenko N, Gomkale R, Schulz C, Guiard B, Chacinska A, Rehling P (2018) Motor recruitment to the TIM23 channel’s lateral gate restricts polypeptide release into the inner membrane. Nat Commun<\/b> 9, 4028.<\/a><\/p>\n

Aich A, Wang C, Chowdhury A, Rons\u00f6r C, Pacheu-Grau D, Richter-Dennerlein R, Dennerlein S, Rehling P (2018) COX16 promotes COX2 metallation and assembly during respiratory complex IV biogenesis. Elife<\/b> 7:e32572.<\/a><\/p>\n

Lorenzi I, Oeljeklaus S, Aich A, Rons\u00f6r C, Callegari S, Dudek J, Warscheid B, Dennerlein S, Rehling P (2018) The mitochondrial TMEM177 associates with COX20 during COX2 biogenesis. Biochim Biophys Acta Mol Cell Res<\/b> 1865, 323-333.<\/a><\/p>\n

Richter KN, Revelo NH, Seitz KJ, Helm MS, Sarkar D, Saleeb RS, D’Este E, Eberle J, Wagner E, Vogl C, Lazaro DF, Richter F, Coy-Vergara J, Coceano G, Boyden ES, Duncan RR, Hell SW, Lauterbach MA, Lehnart SE, Moser T, Outeiro TF, Rehling P, Schwappach B, Testa I, Zapiec B, Rizzoli SO (2018) Glyoxal as an alternative fixative to formaldehyde in immunostaining and super-resolution microscopy. EMBO J<\/b> 37, 139-159.<\/a><\/p>\n

2017<\/b>
\nNaumenko N, Morgenstern M, Ruckt\u00e4schel R, Warscheid B, Rehling P (2017) INA complex liaises the F1<\/sub>Fo<\/sub>-ATP synthase membrane motor modules. Nat Commun<\/b> 8, 1237.<\/a><\/p>\n

Denkert N, Schendzielorz AB, Barbot M, Versemann L, Richter F, Rehling P, Meinecke M (2017) Cation selectivity of the presequence translocase channel Tim23 is crucial for efficient protein import. Elife<\/b> 6:e28324.<\/a><\/p>\n

Dennerlein S, Wang C, Rehling P (2017) Plasticity of Mitochondrial Translation. Trends Cell Biol<\/b> 27, 712-721.<\/a><\/p>\n

Schendzielorz AB, Schulz C, Lytovchenko O, Clancy A, Guiard B, Ieva R, van der Laan M, Rehling P (2017) Two distinct membrane potential-dependent steps drive mitochondrial matrix protein translocation. J Cell Biol<\/b> 216, 83-92.<\/a><\/p>\n

Callegari S, Oeljeklaus S, Warscheid B, Dennerlein S, Thumm M, Rehling P, Dudek J (2017) Phospho-ubiquitin-PARK2 complex as a marker for mitophagy defects. Autophagy<\/b> 13, 201-211.<\/a><\/p>\n

Guentsch A, Beneke A, Swain L, Farhat K, Nagarajan S, Wielockx B, Raithatha K, Dudek J, Rehling P, Zieseniss A, Jatho A, Chong M, Santos CXC, Shah AM, Katschinski DM (2017) PHD2 Is a Regulator for Glycolytic Reprogramming in Macrophages. Mol Cell Biol<\/b> 37(1):e00236-16.<\/a><\/p>\n

2016<\/b>
\nCallegari S, Richter F, Chojnacka K, Jans DC, Lorenzi I, Pacheu-Grau D, Jakobs S, Lenz C, Urlaub H, Dudek J, Chacinska A, Rehling P (2016) TIM29 is a subunit of the human carrier translocase required for protein transport. FEBS Lett<\/b> 590, 4147-4158.<\/a><\/p>\n

Richter-Dennerlein R, Oeljeklaus S, Lorenzi I, Rons\u00f6r C, Bareth B, Schendzielorz AB, Wang C, Warscheid B, Rehling P, Dennerlein S (2016) Mitochondrial Protein Synthesis Adapts to Influx of Nuclear-Encoded Protein. Cell<\/b> 167, 471-483.e10.<\/a><\/p>\n

Lorenzi I, Oeljeklaus S, Rons\u00f6r C, Bareth B, Warscheid B, Rehling P, Dennerlein S (2016) Ribosome-Associated Mba1 Escorts Cox2 from Insertion Machinery to Maturing Assembly Intermediates. Mol Cell Biol<\/b> 36, 2782-2793.<\/a><\/p>\n

Haag S, Sloan KE, Ranjan N, Warda AS, Kretschmer J, Blessing C, H\u00fcbner B, Seikowski J, Dennerlein S, Rehling P, Rodnina MV, H\u00f6bartner C, Bohnsack MT (2016) NSUN3 and ABH1 modify the wobble position of mt-tRNAMet to expand codon recognition in mitochondrial translation. EMBO J<\/b> 35, 2104-2119.<\/a><\/p>\n

Levchenko M, Wuttke JM, R\u00f6mpler K, Schmidt B, Neifer K, Juris L, Wissel M, Rehling P, Deckers M (2016) Cox26 is a novel stoichiometric subunit of the yeast cytochrome c oxidase. Biochim Biophys Acta<\/b> 1863, 1624-1632.<\/a><\/p>\n

Bareth B, Nikolov M, Lorenzi I, Hildenbeutel M, Mick DU, Helbig C, Urlaub H, Ott M, Rehling P, Dennerlein S (2016) Oms1 associates with cytochrome c oxidase assembly intermediates to stabilize newly synthesized Cox1. Mol Biol Cell<\/b> 27, 1570-1580.<\/a><\/p>\n

Heininger AU, Hackert P, Andreou AZ, Boon KL, Memet I, Prior M, Clancy A, Schmidt B, Urlaub H, Schleiff E, Sloan KE, Deckers M, L\u00fchrmann R, Enderlein J, Klostermeier D, Rehling P, Bohnsack MT (2016) Protein cofactor competition regulates the action of a multifunctional RNA helicase in different pathways. RNA Biol<\/b> 13, 320-330.<\/a><\/p>\n

Dudek J, Cheng IF, Chowdhury A, Wozny K, Balleininger M, Reinhold R, Grunau S, Callegari S, Toischer K, Wanders RJ, Hasenfu\u00df G, Br\u00fcgger B, Guan K, Rehling P (2016) Cardiac-specific succinate dehydrogenase deficiency in Barth syndrome. EMBO Mol Med<\/b> 8, 139-154.<\/a><\/p>\n

2015<\/b>
\nRichter-Dennerlein R, Dennerlein S, Rehling P (2015) Integrating mitochondrial translation into the cellular context. Nat Rev Mol Cell Biol<\/b> 16, 586-592.<\/a><\/p>\n

Dennerlein S, Oeljeklaus S, Jans D, Hellwig C, Bareth B, Jakobs S, Deckers M, Warscheid B, Rehling P (2015) MITRAC7 Acts as a COX1-Specific Chaperone and Reveals a Checkpoint during Cytochrome c Oxidase Assembly. Cell Rep<\/b> 12, 1644-1655.<\/a><\/p>\n

Pacheu-Grau D, Bareth B, Dudek J, Juris L, V\u00f6gtle FN, Wissel M, Leary SC, Dennerlein S, Rehling P, Deckers M (2015) Cooperation between COA6 and SCO2 in COX2 maturation during cytochrome c oxidase assembly links two mitochondrial cardiomyopathies. Cell Metab<\/b> 21, 823-833.<\/a><\/p>\n

Melin J, Kilisch M, Neumann P, Lytovchenko O, Gomkale R, Schendzielorz A, Schmidt B, Liepold T, Ficner R, Jahn O, Rehling P, Schulz C (2015) A presequence-binding groove in Tom70 supports import of Mdl1 into mitochondria. Biochim Biophys Acta<\/b> 1853, 1850-1859.<\/a><\/p>\n

Dennerlein S, Rehling P (2015) Human mitochondrial COX1 assembly into cytochrome c oxidase at a glance. J Cell Sci<\/b> 128, 833-837.<\/a><\/p>\n

Schulz C, Schendzielorz A, Rehling P (2015) Unlocking the presequence import pathway. Trends Cell Biol<\/b> 25, 265-275.<\/a><\/p>\n

2014<\/b>
\nSchulz C, Rehling P (2014) Cell biology. Powering the cell cycle. Science<\/b> 346, 1059-1060.<\/a><\/p>\n

Gornicka A, Bragoszewski P, Chroscicki P, Wenz LS, Schulz C, Rehling P, Chacinska A (2014) A discrete pathway for the transfer of intermembrane space proteins across the outer membrane of mitochondria. Mol Biol Cell<\/b> 25, 3999-4009.<\/a><\/p>\n

Schulz C, Rehling P (2014) Remodelling of the active presequence translocase drives motor-dependent mitochondrial protein translocation. Nat Commun<\/b> 5, 4349.<\/a><\/p>\n

Melin J, Schulz C, Wrobel L, Bernhard O, Chacinska A, Jahn O, Schmidt B, Rehling P (2014) Presequence recognition by the tom40 channel contributes to precursor translocation into the mitochondrial matrix. Mol Cell Biol<\/b> 34, 3473-3485.<\/a><\/p>\n

Lytovchenko O, Naumenko N, Oeljeklaus S, Schmidt B, von der Malsburg K, Deckers M, Warscheid B, van der Laan M, Rehling P (2014) The INA complex facilitates assembly of the peripheral stalk of the mitochondrial F1Fo-ATP synthase. EMBO J<\/b> 33, 1624-1638.<\/a><\/p>\n

Pfanner N, van der Laan M, Amati P, Capaldi RA, Caudy AA, Chacinska A, Darshi M, Deckers M, Hoppins S, Icho T, Jakobs S, Ji J, Kozjak-Pavlovic V, Meisinger C, Odgren PR, Park SK, Rehling P, Reichert AS, Sheikh MS, Taylor SS, Tsuchida N, van der Bliek AM, van der Klei IJ, Weissman JS, Westermann B, Zha J, Neupert W, Nunnari J (2014) Uniform nomenclature for the mitochondrial contact site and cristae organizing system. J Cell Biol<\/b> 204, 1083-1086.<\/a><\/p>\n

2013<\/b>
\nBareth B, Dennerlein S, Mick DU, Nikolov M, Urlaub H, Rehling P (2013) The heme a synthase Cox15 associates with cytochrome c oxidase assembly intermediates during Cox1 maturation. Mol Cell Biol<\/b> 33, 4128-4137.<\/a><\/p>\n

Welter E, Montino M, Reinhold R, Schlotterhose P, Krick R, Dudek J, Rehling P, Thumm M (2013) Uth1 is a mitochondrial inner membrane protein dispensable for post-log-phase and rapamycin-induced mitophagy. FEBS J<\/b> 280, 4970-4982.<\/a><\/p>\n

Dudek J, Cheng IF, Balleininger M, Vaz FM, Streckfuss-B\u00f6meke K, H\u00fcbscher D, Vukotic M, Wanders RJ, Rehling P, Guan K (2013) Cardiolipin deficiency affects respiratory chain function and organization in an induced pluripotent stem cell model of Barth syndrome. Stem Cell Res<\/b> 11, 806-819.<\/a><\/p>\n

Jans DC, Wurm CA, Riedel D, Wenzel D, Stagge F, Deckers M, Rehling P, Jakobs S (2013) STED super-resolution microscopy reveals an array of MINOS clusters along human mitochondria. Proc Natl Acad Sci U S A<\/b> 110, 8936-8941.<\/a><\/p>\n

Lytovchenko O, Melin J, Schulz C, Kilisch M, Hutu DP, Rehling P (2013) Signal recognition initiates reorganization of the presequence translocase during protein import. EMBO J<\/b> 32, 886-898.<\/a><\/p>\n

Dudek J, Rehling P, van der Laan M (2013) Mitochondrial protein import: common principles and physiological networks. Biochim Biophys Acta<\/b> 1833, 274-285.<\/a><\/p>\n

2012<\/b>
\nMick DU, Dennerlein S, Wiese H, Reinhold R, Pacheu-Grau D, Lorenzi I, Sasarman F, Weraarpachai W, Shoubridge EA, Warscheid B, Rehling P (2012) MITRAC links mitochondrial protein translocation to respiratory-chain assembly and translational regulation. Cell<\/b> 151, 1528-1541.<\/a><\/p>\n

Reinhold R, Kr\u00fcger V, Meinecke M, Schulz C, Schmidt B, Grunau SD, Guiard B, Wiedemann N, van der Laan M, Wagner R, Rehling P, Dudek J (2012) The channel-forming Sym1 protein is transported by the TIM23 complex in a presequence-independent manner. Mol Cell Biol<\/b> 32, 5009-5021.<\/a><\/p>\n

Keil M, Bareth B, Woellhaf MW, Peleh V, Prestele M, Rehling P, Herrmann JM (2012) Oxa1-ribosome complexes coordinate the assembly of cytochrome C oxidase in mitochondria. J Biol Chem<\/b> 287, 34484-34493.<\/a><\/p>\n

Kr\u00fcger V, Deckers M, Hildenbeutel M, van der Laan M, Hellmers M, Dreker C, Preuss M, Herrmann JM, Rehling P, Wagner R, Meinecke M (2012) The mitochondrial oxidase assembly protein1 (Oxa1) insertase forms a membrane pore in lipid bilayers. J Biol Chem<\/b> 287, 33314-33326.<\/a><\/p>\n

Vukotic M, Oeljeklaus S, Wiese S, V\u00f6gtle FN, Meisinger C, Meyer HE, Zieseniss A, Katschinski DM, Jans DC, Jakobs S, Warscheid B, Rehling P, Deckers M (2012) Rcf1 mediates cytochrome oxidase assembly and respirasome formation, revealing heterogeneity of the enzyme complex. Cell Metab<\/b> 15, 336-347.<\/a><\/p>\n

2011<\/b>
\nGebert N, Gebert M, Oeljeklaus S, von der Malsburg K, Stroud DA, Kulawiak B, Wirth C, Zahedi RP, Dolezal P, Wiese S, Simon O, Schulze-Specking A, Truscott KN, Sickmann A, Rehling P, Guiard B, Hunte C, Warscheid B, van der Laan M, Pfanner N, Wiedemann N (2011) Dual function of Sdh3 in the respiratory chain and TIM22 protein translocase of the mitochondrial inner membrane. Mol Cell<\/b> 44, 811-818.<\/a><\/p>\n

Schulz C, Lytovchenko O, Melin J, Chacinska A, Guiard B, Neumann P, Ficner R, Jahn O, Schmidt B, Rehling P (2011) Tim50’s presequence receptor domain is essential for signal driven transport across the TIM23 complex. J Cell Biol<\/b> 195, 643-656.<\/a><\/p>\n

von der Malsburg K, M\u00fcller JM, Bohnert M, Oeljeklaus S, Kwiatkowska P, Becker T, Loniewska-Lwowska A, Wiese S, Rao S, Milenkovic D, Hutu DP, Zerbes RM, Schulze-Specking A, Meyer HE, Martinou JC, Rospert S, Rehling P, Meisinger C, Veenhuis M, Warscheid B, van der Klei IJ, Pfanner N, Chacinska A, van der Laan M (2011) Dual role of mitofilin in mitochondrial membrane organization and protein biogenesis. Dev Cell<\/b> 21, 694-707.<\/a><\/p>\n

Lupo D, Vollmer C, Deckers M, Mick DU, Tews I, Sinning I, Rehling P (2011) Mdm38 is a 14-3-3-like receptor and associates with the protein synthesis machinery at the inner mitochondrial membrane. Traffic<\/b> 12, 1457-1466.<\/a><\/p>\n

Rehling P (2011) Tinkering with nature. Nat Rev Mol Cell Biol<\/b> 12, 401.<\/a><\/p>\n

Reinhold R, Bareth B, Balleininger M, Wissel M, Rehling P, Mick DU (2011) Mimicking a SURF1 allele reveals uncoupling of cytochrome c oxidase assembly from translational regulation in yeast. Hum Mol Genet<\/b> 20, 2379-2393.<\/a><\/p>\n

Mick DU, Fox TD, Rehling P (2011) Inventory control: cytochrome c oxidase assembly regulates mitochondrial translation. Nat Rev Mol Cell Biol<\/b> 12, 14-20.<\/a><\/p>\n

2010<\/b>
\nMick DU, Vukotic M, Piechura H, Meyer HE, Warscheid B, Deckers M, Rehling P (2010) Coa3 and Cox14 are essential for negative feedback regulation of COX1 translation in mitochondria. J Cell Biol<\/b> 191, 141-154.<\/a><\/p>\n

Bohnert M, Rehling P, Guiard B, Herrmann JM, Pfanner N, van der Laan M (2010) Cooperation of stop-transfer and conservative sorting mechanisms in mitochondrial protein transport. Curr Biol<\/b> 20, 1227-1232.<\/a><\/p>\n

Rehling P, Rospert S (2010) Molecular chaperones and intracellular protein transport. Biochim Biophys Acta<\/b> 1803, 639-640.<\/a><\/p>\n

Bauerschmitt H, Mick DU, Deckers M, Vollmer C, Funes S, Kehrein K, Ott M, Rehling P, Herrmann JM (2010) Ribosome-binding proteins Mdm38 and Mba1 display overlapping functions for regulation of mitochondrial translation. Mol Biol Cell<\/b> 21, 1937-1944.<\/a><\/p>\n

van der Laan M, Hutu DP, Rehling P (2010) On the mechanism of preprotein import by the mitochondrial presequence translocase. Biochim Biophys Acta<\/b> 1803, 732-739.<\/a><\/p>\n

Chacinska A, van der Laan M, Mehnert CS, Guiard B, Mick DU, Hutu DP, Truscott KN, Wiedemann N, Meisinger C, Pfanner N, Rehling P (2010) Distinct forms of mitochondrial TOM-TIM supercomplexes define signal-dependent states of preprotein sorting. Mol Cell Biol<\/b> 30, 307-318.<\/a><\/p>\n

2009<\/b>
\nGebert N, Joshi AS, Kutik S, Becker T, McKenzie M, Guan XL, Mooga VP, Stroud DA, Kulkarni G, Wenk MR, Rehling P, Meisinger C, Ryan MT, Wiedemann N, Greenberg ML, Pfanner N (2009) Mitochondrial cardiolipin involved in outer-membrane protein biogenesis: implications for Barth syndrome. Curr Biol<\/b> 19, 2133-2139.<\/a><\/p>\n

Wagner K, Rehling P, Sanju\u00e1n Szklarz LK, Taylor RD, Pfanner N, van der Laan M (2009) Mitochondrial F1Fo-ATP synthase: the small subunits e and g associate with monomeric complexes to trigger dimerization. J Mol Biol<\/b> 392, 855-861.<\/a><\/p>\n

Odorizzi G, Rehling P (2009) Membranes and organelles. Curr Opin Cell Biol<\/b> 21, 481-483.<\/a><\/p>\n

Wagner K, Mick DU, Rehling P (2009) Protein transport machineries for precursor translocation across the inner mitochondrial membrane. Biochim Biophys Acta<\/b> 1793, 52-59.<\/a><\/p>\n

2008<\/b>
\nKutik S, Rissler M, Guan XL, Guiard B, Shui G, Gebert N, Heacock PN, Rehling P, Dowhan W, Wenk MR, Pfanner N, Wiedemann N (2008) The translocator maintenance protein Tam41 is required for mitochondrial cardiolipin biosynthesis. J Cell Biol<\/b> 183, 1213-1221.<\/a><\/p>\n

Wagner K, Gebert N, Guiard B, Brandner K, Truscott KN, Wiedemann N, Pfanner N, Rehling P (2008) The assembly pathway of the mitochondrial carrier translocase involves four preprotein translocases. Mol Cell Biol<\/b> 28, 4251-4260.<\/a><\/p>\n

Gebert N, Chacinska A, Wagner K, Guiard B, Koehler CM, Rehling P, Pfanner N, Wiedemann N (2008) Assembly of the three small Tim proteins precedes docking to the mitochondrial carrier translocase. EMBO Rep<\/b> 9, 548-554.<\/a><\/p>\n

Hutu DP, Guiard B, Chacinska A, Becker D, Pfanner N, Rehling P, van der Laan M (2008) Mitochondrial protein import motor: differential role of Tim44 in the recruitment of Pam17 and J-complex to the presequence translocase. Mol Biol Cell<\/b> 19, 2642-2649.<\/a><\/p>\n

Stuart RA, Rehling P (2008) Mitochondrial biogenesis: is an old dog still teaching us new tricks? Meeting on the Assembly of the Mitochondrial Respiratory Chain. EMBO Rep<\/b> 9, 33-38.<\/a><\/p>\n

2007<\/b>
\nWiedemann N, van der Laan M, Hutu DP, Rehling P, Pfanner N (2007) Sorting switch of mitochondrial presequence translocase involves coupling of motor module to respiratory chain. J Cell Biol<\/b> 179, 1115-1122.<\/a><\/p>\n

Mick DU, Wagner K, van der Laan M, Frazier AE, Perschil I, Pawlas M, Meyer HE, Warscheid B, Rehling P (2007) Shy1 couples Cox1 translational regulation to cytochrome c oxidase assembly. EMBO J<\/b> 26, 4347-4358.<\/a><\/p>\n

van der Laan M, Meinecke M, Dudek J, Hutu DP, Lind M, Perschil I, Guiard B, Wagner R, Pfanner N, Rehling P (2007) Motor-free mitochondrial presequence translocase drives membrane integration of preproteins. Nat Cell Biol<\/b> 9, 1152-1159.<\/a><\/p>\n

Reinders J, Wagner K, Zahedi RP, Stojanovski D, Eyrich B, van der Laan M, Rehling P, Sickmann A, Pfanner N, Meisinger C (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics<\/b> 6, 1896-1906.<\/a><\/p>\n

2006<\/b>
\nvan der Laan M, Wiedemann N, Mick DU, Guiard B, Rehling P, Pfanner N (2006) A role for Tim21 in membrane-potential-dependent preprotein sorting in mitochondria. Curr Biol<\/b> 16, 2271-2276.<\/a><\/p>\n

Albrecht R, Rehling P, Chacinska A, Brix J, Cadamuro SA, Volkmer R, Guiard B, Pfanner N, Zeth K (2006) The Tim21 binding domain connects the preprotein translocases of both mitochondrial membranes. EMBO Rep<\/b> 7, 1233-1238.<\/a><\/p>\n

van der Laan M, Rissler M, Rehling P (2006) Mitochondrial preprotein translocases as dynamic molecular machines. FEMS Yeast Res<\/b> 6, 849-861.<\/a><\/p>\n

Meinecke M, Wagner R, Kovermann P, Guiard B, Mick DU, Hutu DP, Voos W, Truscott KN, Chacinska A, Pfanner N, Rehling P (2006) Tim50 maintains the permeability barrier of the mitochondrial inner membrane. Science<\/b> 312, 1523-1526.<\/a><\/p>\n

Frazier AE, Taylor RD, Mick DU, Warscheid B, Stoepel N, Meyer HE, Ryan MT, Guiard B, Rehling P (2006) Mdm38 interacts with ribosomes and is a component of the mitochondrial protein export machinery. J Cell Biol<\/b> 172, 553-564.<\/a><\/p>\n

Wiedemann N, Pfanner N, Rehling P (2006) Import of precursor proteins into isolated yeast mitochondria. Methods Mol Biol<\/b> 313, 373-383.<\/a><\/p>\n

2005<\/b>
\nBrandner K, Mick DU, Frazier AE, Taylor RD, Meisinger C, Rehling P (2005) Taz1, an outer mitochondrial membrane protein, affects stability and assembly of inner membrane protein complexes: implications for Barth Syndrome. Mol Biol Cell<\/b> 16, 5202-5214.<\/a><\/p>\n

van der Laan M, Chacinska A, Lind M, Perschil I, Sickmann A, Meyer HE, Guiard B, Meisinger C, Pfanner N, Rehling P (2005) Pam17 is required for architecture and translocation activity of the mitochondrial protein import motor. Mol Cell Biol<\/b> 25, 7449-7458.<\/a><\/p>\n

Chacinska A, Lind M, Frazier AE, Dudek J, Meisinger C, Geissler A, Sickmann A, Meyer HE, Truscott KN, Guiard B, Pfanner N, Rehling P (2005) Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17. Cell<\/b> 120, 817-829.<\/a><\/p>\n

Brandner K, Rehling P, Truscott KN (2005) The carboxyl-terminal third of the dicarboxylate carrier is crucial for productive association with the inner membrane twin-pore translocase. J Biol Chem<\/b> 280, 6215-6221.<\/a><\/p>\n

2004<\/b>
\nRehling P, Brandner K, Pfanner N (2004) Mitochondrial import and the twin-pore translocase. Nat Rev Mol Cell Biol<\/b> 5, 519-530.<\/a><\/p>\n

Li Y, Dudek J, Guiard B, Pfanner N, Rehling P, Voos W (2004) The presequence translocase-associated protein import motor of mitochondria. Pam16 functions in an antagonistic manner to Pam18. J Biol Chem<\/b> 279, 38047-38054.<\/a><\/p>\n

Frazier AE, Dudek J, Guiard B, Voos W, Li Y, Lind M, Meisinger C, Geissler A, Sickmann A, Meyer HE, Bilanchone V, Cumsky MG, Truscott KN, Pfanner N, Rehling P (2004) Pam16 has an essential role in the mitochondrial protein import motor. Nat Struct Mol Biol<\/b> 11, 226-233.<\/a><\/p>\n

2003<\/b>
\nTruscott KN, Voos W, Frazier AE, Lind M, Li Y, Geissler A, Dudek J, M\u00fcller H, Sickmann A, Meyer HE, Meisinger C, Guiard B, Rehling P, Pfanner N (2003) A J-protein is an essential subunit of the presequence translocase-associated protein import motor of mitochondria. J Cell Biol<\/b> 163, 707-713.<\/a><\/p>\n

Sickmann A, Reinders J, Wagner Y, Joppich C, Zahedi R, Meyer HE, Sch\u00f6nfisch B, Perschil I, Chacinska A, Guiard B, Rehling P, Pfanner N, Meisinger C (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A<\/b> 100, 13207-13212.<\/a><\/p>\n

Frazier AE, Chacinska A, Truscott KN, Guiard B, Pfanner N, Rehling P (2003) Mitochondria use different mechanisms for transport of multispanning membrane proteins through the intermembrane space. Mol Cell Biol<\/b> 23, 7818-7828.<\/a><\/p>\n

Chacinska A, Rehling P, Guiard B, Frazier AE, Schulze-Specking A, Pfanner N, Voos W, Meisinger C (2003) Mitochondrial translocation contact sites: separation of dynamic and stabilizing elements in formation of a TOM-TIM-preprotein supercomplex. EMBO J<\/b> 22, 5370-5381.<\/a><\/p>\n

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Rehling P, Pfanner N, Meisinger C (2003) Insertion of hydrophobic membrane proteins into the inner mitochondrial membrane–a guided tour. J Mol Biol<\/b> 326, 639-657.<\/a><\/p>\n<\/div><\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"folder":[83],"class_list":["post-4591","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/biochemie.uni-goettingen.de\/index.php\/wp-json\/wp\/v2\/pages\/4591","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/biochemie.uni-goettingen.de\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/biochemie.uni-goettingen.de\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/biochemie.uni-goettingen.de\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/biochemie.uni-goettingen.de\/index.php\/wp-json\/wp\/v2\/comments?post=4591"}],"version-history":[{"count":47,"href":"https:\/\/biochemie.uni-goettingen.de\/index.php\/wp-json\/wp\/v2\/pages\/4591\/revisions"}],"predecessor-version":[{"id":8286,"href":"https:\/\/biochemie.uni-goettingen.de\/index.php\/wp-json\/wp\/v2\/pages\/4591\/revisions\/8286"}],"wp:attachment":[{"href":"https:\/\/biochemie.uni-goettingen.de\/index.php\/wp-json\/wp\/v2\/media?parent=4591"}],"wp:term":[{"taxonomy":"folder","embeddable":true,"href":"https:\/\/biochemie.uni-goettingen.de\/index.php\/wp-json\/wp\/v2\/folder?post=4591"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}