Afelik S., Chen Y., Pieler T.(2006) Combined ectopic expression of Pdx1 and Ptf1a/p48 results in the stable conversion of posterior endoderm into endocrine and exocrine pancreatic tissue. GENE DEV, 20: 1441-6.

Borchers A., Fonar Y., Frank D., Baker J.C.(2006) XNF-ATc3 affects neural convergent extension. DEVELOPMENT, 133: 1745-55.

Cartry J., Nichane M., Ribes V., Colas A., Riou J.F., Pieler T., Dollé P., Bellefroid E.J., Umbhauer M.(2006) Retinoic acid signalling is required for specification of pronephric cell fate. DEV BIOL, 299: 35-51.

Dudas J., Elmaouhoub A., Mansuroglu T., Batusic D., Tron K., Saile B., Papoutsi M., Pieler T., Wilting J., Ramadori G.(2006) Prospero-related homeobox 1 (Prox1) is a stable hepatocyte marker during liver development, injury and regeneration, and is absent from "oval cells". HISTOCHEM CELL BIOL, 126: 549-562.

Horvay K., Claußen M., Katzer M., Landgrebe J., Pieler T.(2006) Xenopus Dead end mRNA is a localized maternal determinant that serves a conserved function in germ cell development. DEV BIOL, 291: 1-11.

Klisch T.J., Souopgui J., Juergens K., Rust B., Pieler T., Henningfeld K.A.(2006) Mxi1 is essential for neurogenesis in Xenopus and acts by bridging the pan-neural and proneural genes. DEV BIOL, 292: 470-85 Epub 2006 Feb 2.

Koebernick K., Kashef J., Pieler T., Wedlich D.(2006) Xenopus Teashirt1 regulates posterior identity in brain and cranial neural crest. DEV BIOL, 298: 312-26.

Pan F.C., Chen Y., Loeber J., Henningfeld K., Pieler T.(2006) I-SceI meganuclease-mediated transgenesis in Xenopus. DEV DYNAM, 235: 247-52.

Pieler T., Chen Y.(2006) Forgotten and novel aspects in pancreas development. BIOL CELL, 98: 79-88.

Sölter M., Locker M., Boy S., Taelman V., Bellefroid E.J., Perron M., Pieler T.(2006) Characterization and function of the bHLH-O protein XHes2: insight into the mechanisms controlling retinal cell fate decision. DEVELOPMENT, 133: 4097-108.

Taelman V., Van Campenhout C., Sölter M., Pieler T., Bellefroid E.J.(2006) The Notch-effector HRT1 gene plays a role in glomerular development and patterning of the Xenopus pronephros anlagen. DEVELOPMENT, 133: 2961-71.

Hollemann T., Chen Y., Sölter M., Kühl M., Pieler T.(2006) Embryonic explants from Xenopus laevis as an assay system to study differentiation of multipotent precursor cells. In: Celis, J.E. (Hg.) Academic Press, Elsevier Science, San Diego, 191-198.

Pieler T., Pan F.C., Afelik S., Chen Y.(2006) Molecular genetics of Liver and Pancreas Development. In: Unsicker K. and Krieglstein, K. (Hg.) Wiley-VCH Verlag, England, 823-840.

Cimica V., Batusic D., Haralanova-Ilieva B., Chen Y., Hollemann T., Pieler T., Ramadori G.(2007) Serial analysis of gene expression (SAGE) in rat liver regeneration. BIOCHEM BIOPH RES CO, 360: 545-52.

Dullin J.P., Locker M., Robach M., Henningfeld K.A., Parain K., Afelik S., Pieler T., Perron M.(2007) Ptf1a triggers GABAergic neuronal cell fates in the retina. BMC DEV BIOL, 7: 110.

Hollemann T., Tadjuidje E., Koebernick K., Pieler T.(2007) Manipulation of hedgehog signaling in Xenopus by means of embryo microinjection and application of chemical inhibitors. Methods Mol Biol, 397: 35-46.

Hou S., Maccarana M., Min T.H., Strate I., Pera E.M.(2007) The secreted serine protease xHtrA1 stimulates long-range FGF signaling in the early Xenopus embryo. DEV CELL, 13: 226-41.

Pan F.C., Chen Y., Bayha E., Pieler T.(2007) Retinoic acid-mediated patterning of the pre-pancreatic endoderm in Xenopus operates via direct and indirect mechanisms. MECH DEVELOP, 124: 518-31.

Papoutsi M., Dudas J., Becker J., Tripodi M., Opitz L., Ramadori G., Wilting J.(2007) Gene regulation by homeobox transcription factor Prox1 in murine hepatoblasts. CELL TISSUE RES, 330: 209-20.

Souopgui J., Klisch T.J., Pieler T., Henningfeld K.A.(2007) Expression and regulation of Xenopus CRMP-4 in the developing nervous system. INT J DEV BIOL, 51: 339-43.

Tarbashevich K., Koebernick K., Pieler T.(2007) XGRIP2.1 is encoded by a vegetally localizing, maternal mRNA and functions in germ cell development and anteroposterior PGC positioning in Xenopus laevis. DEV BIOL, 311: 554-65.

Henningfeld K.A., Locker M., Perron M.(2007) Xenopus primary neurogenesis and retinogenesis. In: Jaime A. Teixeira da Silva (Hg.) Global Science Books Verlag, England, 26-36.

Chesneau A., Sachs L.M., Chai N., Chen Y., Du Pasquier L., Loeber J., Pollet N., Reilly M., Weeks D.L., Bronchain O.J.(2008) Transgenesis procedures in Xenopus. BIOL CELL, 100: 503-21.

Fialka F., Gruber R.M., Hitt R., Opitz L., Brunner E., Schliephake H., Kramer F.J.(2008) CPA6, FMO2, LGI1, SIAT1 and TNC are differentially expressed in early- and late-stage oral squamous cell carcinoma - A pilot study. ORAL ONCOL, 44: 941-8.

Kippert A., Trajkovic K., Fitzner D., Opitz L., Simons M.(2008) Identification of Tmem10/Opalin as a novel marker for oligodendrocytes using gene expression profiling. BMC NEUROSCI, 9: 40.

Koestner U., Shnitsar I., Linnemannstöns K., Hufton Andrew L., Borchers A.(2008) Semaphorin and neuropilin expression during early morphogenesis of Xenopus laevis. DEV DYNAM, 237: 3853-63.

McSharry B.P., Burgert H.G., Owen D.P., Stanton R.J., Prod'homme V., Sester M., Koebernick K., Groh V., Spies T., Cox S., Little A.M., Wang E.C.Y., Tomasec P., Wilkinson G.W.G.(2008) Adenovirus E3/19K promotes evasion of NK cell recognition by intracellular sequestration of the NKG2D ligands major histocompatibility complex class I chain-related proteins A and B. J VIROL, 82: 4585-94.

Meinicke P., Lingner T., Kaever A., Feussner K., Göbel C., Feussner I., Karlovsky P., Morgenstern B.(2008) Metabolite-based clustering and visualization of mass spectrometry data using one-dimensional self-organizing maps. ALGORITHM MOL BIOL, 3: 1-18.

Menz B., Sester M., Koebernick K., Schmid R., Burgert H.G.(2008) Structural analysis of the adenovirus type 2 E3/19K protein using mutagenesis and a panel of conformation-sensitive monoclonal antibodies. MOL IMMUNOL, 46: 16-26.

Schallus T., Jaeckh C., Fehér K., Palma A.S., Liu Y., Simpson J.C., Mackeen M., Stier G., Gibson T.J., Feizi T., Pieler T., Muhle-Goll C.(2008) Malectin: a novel carbohydrate-binding protein of the endoplasmic reticulum and a candidate player in the early steps of protein N-glycosylation. MOL BIOL CELL, 19: 3404-14.

Shnitsar I., Borchers A.(2008) PTK7 recruits dsh to regulate neural crest migration. DEVELOPMENT, 135: 4015-24.

Souopgui J., Rust B., Vanhomwegen J., Heasman J., Henningfeld K.A., Bellefroid E., Pieler T.(2008) The RNA-binding protein XSeb4R: a positive regulator of VegT mRNA stability and translation that is required for germ layer formation in Xenopus. GENE DEV, 22: 2347-52.

Arthur P.K., Claußen M., Koch S., Tarbashevich K., Jahn O., Pieler T.(2009) Participation of Xenopus Elr-type proteins in vegetal mRNA localization during oogenesis. J BIOL CHEM, 284: 19982-92.

Damianitsch K., Melchert J., Pieler T.(2009) XsFRP5 modulates endodermal organogenesis in Xenopus laevis. Dev Biol (Internet-Ausgabe), 329: 327-37.

El Bounkari O., Guria A., Klebba-Faerber S., Claußen M., Pieler T., Griffiths J.R., Whetton A.D., Koch A., Tamura T.(2009) Nuclear localization of the pre-mRNA associating protein THOC7 depends upon its direct interaction with Fms tyrosine kinase interacting protein (FMIP). Febs Lett (Internet-Ausgabe), 583: 13-8.

Galli S., Jahn O., Hitt R., Hesse D., Opitz L., Plessmann U., Urlaub H., Poderoso J.J., Jares-Erijman E.A., Jovin T.M.(2009) A new paradigm for MAPK: structural interactions of hERK1 with mitochondria in HeLa cells. PLOS ONE, 4: e7541.

Henneke M., Diekmann S., Ohlenbusch A., Kaiser J., Engelbrecht V., Kohlschütter A., Krätzner R., Madruga-Garrido M., Mayer M., Opitz L., Rodriguez D., Rüschendorf F., Schumacher J., Thiele H., Thoms S., Steinfeld R., Nürnberg P., Gärtner J.(2009) RNASET2-deficient cystic leukoencephalopathy resembles congenital cytomegalovirus brain infection. Nat Genet (Internet-Ausgabe), 41: 773-5.

Kaever A., Lingner T., Feussner K., Göbel C., Feussner I., Meinicke P.(2009) MarVis: a tool for clustering and visualization of metabolic biomarkers. BMC BIOINFORMATICS, 10: 92.

Loeber J., Pan F.C., Pieler T.(2009) Generation of transgenic frogs. Methods Mol Biol, 561: 65-72.

Montag J., Hitt R., Opitz L., Schulz-Schaeffer W.J., Hunsmann G., Motzkus D.(2009) Upregulation of miRNA hsa-miR-342-3p in experimental and idiopathic prion disease. MOL NEURODEGENER, 4: 36.

Nieber F., Pieler T., Henningfeld K.A.(2009) Comparative expression analysis of the neurogenins in Xenopus tropicalis and Xenopus laevis. DEV DYNAM, 238: 451-8.

Petrova D.T., Heller T., Hitt R., Wieland E., Oellerich M., Armstrong V.W., Shipkova M.(2009) Regulation of IL2 and NUCB1 in mononuclear cells treated with acyl glucuronide of mycophenolic acid reveals effects independent of inosine monophosphate dehydrogenase inhibition. THER DRUG MONIT, 31: 31-41.

Strate I., Min T.H., Iliev D., Pera E.M.(2009) Retinol dehydrogenase 10 is a feedback regulator of retinoic acid signalling during axis formation and patterning of the central nervous system. DEVELOPMENT, 136: 461-72.

Auber B., Burfeind P., Thiels C., Alsat E.A., Shoukier M., Liehr T., Nelle H., Bartels I., Salinas-Riester G., Laccone F.(2010) An unbalanced translocation resulting in a duplication of Xq28 causes a Rett syndrome-like phenotype in a female patient. Clin Genet (Internet-Ausgabe), 77: 593-7.

Brennan C., Dosch R., Haramis A.P., Luckenbach T., Martinez-Morales J.R., Moro E., Polok B., Ramesh T.M., Russell C., Argenton F., Strähle U.(2010) Report of the European Zebrafish Principal Investigator Meeting in Padua, Italy, March 18–22, 2010. ZEBRAFISH, 7: 305-10.

Budde H., Schmitt S., Fitzner D., Opitz L., Salinas-Riester G., Simons M.(2010) Control of oligodendroglial cell number by the miR-17-92 cluster. DEVELOPMENT, 137: 2127-32.

Claussen M., Pieler T.(2010) Identification of vegetal RNA-localization elements in Xenopus oocytes. METHODS, 51: 146-51.

Drewelus I., Göpfert C., Hippel C., Dickmanns A., Damianitsch K., Pieler T., Dobbelstein M.(2010) p63 antagonizes Wnt-induced transcription. Cell Cycle (Internet-Ausgabe), 9: 580-87.

Hesse A., Wagner M., Held J., Brück W., Salinas-Riester G., Hao Z., Waisman A., Kuhlmann T.(2010) In toxic demyelination oligodendroglial cell death occurs early and is FAS independent. Neurobiol Dis (Internet-Ausgabe), 37: 362-9.

Jung K., Grade M., Gaedcke J., Jo P., Opitz L., Becker H., Ghadimi B.M., Beißbarth T.(2010) A new sensitivity-preferred strategy to build prediction rules for therapy response of cancer patients using gene expression data. Comput Meth Prog Bio (Internet-Ausgabe), 100: 132-9.

Koebernick K., Loeber J., Arthur P.K., Tarbashevich K., Pieler T.(2010) Elr-type proteins protect Xenopus Dead end mRNA from miR-18-mediated clearance in the soma. P Natl Acad Sci USA (Internet-Ausgabe), 107: 16148-53.

Loeber J., Claussen M., Jahn O., Pieler T.(2010) Interaction of 42Sp50 with the vegetal RNA localization machinery in Xenopus laevis oocytes. Febs J (Internet-Ausgabe), 277: 4722-31.

Meyer S., Nolte J., Opitz L., Salinas-Riester G., Engel W.(2010) Pluripotent embryonic stem cells and multipotent adult germline stem cells reveal similar transcriptomes including pluripotency-related genes. Mol Hum Reprod (Internet-Ausgabe), 16: 846-55.

Nahlik K., Dumkow M., Bayram O., Helmstaedt K., Busch S., Valerius O., Gerke J., Hoppert M., Schwier E., Opitz L., Westermann M., Grond S., Feussner K., Goebel C., Kaever A., Meinicke P., Feussner I., Braus G.H.(2010) The COP9 signalosome mediates transcriptional and metabolic response to hormones, oxidative stress protection and cell wall rearrangement during fungal development. Mol Microbiol (Internet-Ausgabe), 78: 964-79.

Opitz L., Salinas-Riester G., Grade M., Jung K., Jo P., Emons G., Ghadimi B.M., Beissbarth T., Gaedcke J.(2010) Impact of RNA degradation on gene expression profiling. BMC MED GENOMICS, 3: 36.

Peleg S., Sananbenesi F., Zovoilis A., Burkhardt S., Bahari-Javan S., Agis-Balboa R.C., Cota P., Wittnam J.L., Gogol-Doering A., Opitz L., Salinas-Riester G., Dettenhofer M., Kang H., Farinelli L., Chen W., Fischer A.(2010) Altered histone acetylation is associated with age-dependent memory impairment in mice. Science (Internet-Ausgabe), 328: 753-6.

Polychronidou M., Hellwig A., Grosshans J.(2010) Farnesylated nuclear proteins Kugelkern and lamin Dm0 affect nuclear morphology by directly interacting with the nuclear membrane. Mol Biol Cell (Internet-Ausgabe), 21: 3409-20.

Rohrbeck A., Salinas G., Maaser K., Linge J., Salovaara S., Corvi R., Borlak J.(2010) Toxicogenomics applied to in vitro carcinogenicity testing with Balb/c 3T3 cells revealed a gene signature predictive of chemical carcinogens. TOXICOL SCI, 118: 31-41.

Wagner G., Peradziryi H., Wehner P., Borchers A.(2010) PlexinA1 interacts with PTK7 and is required for neural crest migration. BIOCHEM BIOPH RES CO, 402: 402-7.

Wenzl C., Yan S., Laupsien P., Grosshans J.(2010) Localization of RhoGEF2 during Drosophila cellularization is developmentally controlled by Slam. MECH DEVELOP, 127: 371-84.

Zovoilis A., Pantazi A., Smorag L., Opitz L., Riester G.S., Wolf M., Zechner U., Holubowska A., Stewart C.L., Engel W.(2010) Embryonic stem cell-related miRNAs are involved in differentiation of pluripotent cells originating from the germ line. Mol Hum Reprod (Internet-Ausgabe), 16: 793-803.

Agis-Balboa R.C., Arcos-Diaz D., Wittnam J., Govindarajan N., Blom K., Burkhardt S., Haladyniak U., Agbemenyah H.Y., Zovoilis A., Salinas-Riester G., Opitz L., Sananbenesi F., Fischer A.(2011) A hippocampal insulin-growth factor 2 pathway regulates the extinction of fear memories. Embo J (Internet-Ausgabe), 30: 4071-83.

Bontems F., Baerlocher L., Mehenni S., Bahechar I., Farinelli L., Dosch R.(2011) Efficient mutation identification in zebrafish by microarray capturing and next generation sequencing. BIOCHEM BIOPH RES CO, 405: 373-6.

Claußen M., Tarbashevich K., Pieler T.(2011) Functional dissection of the RNA signal sequence responsible for vegetal localization of XGrip2.1 mRNA in Xenopus oocytes. RNA BIOL, 8: 873-882.

Fort A., Fish R.J., Attanasio C., Dosch R., Visel A., Neerman-Arbez M.(2011) A liver enhancer in the fibrinogen gene cluster. Blood (Internet-Ausgabe), 117: 276-82.

Kanesaki T., Edwards C.M., Schwarz U.S., Grosshans J.(2011) Dynamic ordering of nuclei in syncytial embryos: a quantitative analysis of the role of cytoskeletal networks. INTEGR BIOL-UK, 3: 1112-9.

Novota P., Zinöcker S., Norden J., Wang X.N., Sviland L., Opitz L., Salinas-Riester G., Rolstad B., Dickinson A.M., Walter L., Dressel R.(2011) Expression profiling of major histocompatibility and natural killer complex genes reveals candidates for controlling risk of graft versus host disease. PLOS ONE, 6: e16582.

Peradziryi H., Kaplan N.A., Podleschny M., Liu X., Wehner P., Borchers A., Tolwinski N.S.(2011) PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling. Embo J (Internet-Ausgabe), 30: 3729-40.

Polychronidou M., Großhans J.(2011) Determining nuclear shape: the role of farnesylated nuclear membrane proteins. Nucleus, 2: 17-23.

Shoukier M., Wickert J., Schröder J., Bartels I., Auber B., Zoll B., Salinas-Riester G., Weise D., Brockmann K., Zirn B., Burfeind P.(2011) A 16q12 microdeletion in a boy with severe psychomotor delay, craniofacial dysmorphism, brain and limb malformations, and a heart defect. Am J Med Genet A (Internet-Ausgabe), 32: 251-265.

Tarbashevich K., Dzementsei A., Pieler T.(2011) A novel function for KIF13B in germ cell migration. Dev Biol (Internet-Ausgabe), 349: 169-78.

Wehner P., Shnitsar I., Urlaub H., Borchers A.(2011) RACK1 is a novel interaction partner of PTK7 that is required for neural tube closure. DEVELOPMENT, 138: 1321-7.

Zhao, H., Han, D., Dawid, I.B., Pieler, T. and Chen, Y. (2012) hhex induced conversion of intestinal to ventral pancreatic precursors results in the formation of giant pancreata in Xenopus embryos. PNAS, 109, 8594-8599

Studencka M., Konzer A., Moneron G., Wenzel D., Opitz L., Salinas-Riester G., Bedet C., Krüger M., Hell S.W., Wisniewski J.R., Schmidt H., Palladino F., Schulze E., Jedrusik-Bode M.(2012) Novel roles of Caenorhabditis elegans heterochromatin protein HP1 and linker histone in the regulation of innate immune gene expression. Mol Cell Biol (Internet-Ausgabe), 32: 251-65.

Paul, V., Tonchev, A.B., Henningfeld, K.A., Pavlakis, E., Rust, B., Pieler, T. and Stoykova, A. (2012) Scratch2 Modulates Neurogenesis and Cell Migration Through Antagonism of bHLH Proteins in the Developine Neocortex. Cereb. Cortex (online)

Zhao, H., Han, D., Dawid, I.B., Pieler, T. and Chen, Y. (2012) Homeoprotein hhex induced conversion of intestinal to ventral pancreatic precursos results in the formation of giant pancreata in Xenopus embryos. PNAS 109, 8594-8599.


Hanotel, J., Bessodes, N., Thelie, A., Hedderich, M., Parain, K., Van Driessche, B., Brandao Kde, O., Kricha, S., Jogenson, M.C., Grapin-Botton, A., Serup, P., Van Lint, C., Perron, M., Pieler, T., Henningfeld, K.A. and Bellefroid, E.J. (2013) The Prdm13 histone methyltransferase endoding gene ist a Ptf-1a-Rbpj downstream target that suppresses glutamergic and promotes GABAergic neuronal fate in the dorsal neural tube. Dev. Biol. 386, 1279-1287.

Dzementsei, A., Schneider, D., Janshoff, A. and Pieler, T. (2013) Migratory and adhesive properties of Xenopus laevis primordial germ cells in vitro. Biol. Open 2, 1279-1287.

Nieber, F., Hedderich, M., Jahn, O., Pieler, T. and Henningfeld, K.A. (2013) NumbL is essential for Xenopus primary neurogenesis. BMC Dev. Biol. 238, 13, 36.


Young, T., Poobalan, Y., Tan, E.K., Tao, S., Ong, S., Wehner, P., Schwenty-Lara, J., Lim, C.Y., Sadasivam, A., Lovatt, M., Wang, S.T., Ali, Y., Borchers, A, Sampath, K. and Dunn, N.R. (2014) The PDZ domain protein Mcc is a novel effector of non-canonical Wnt signaling during convergence and extension in zebrafish. Development 141, 3505-3516.

Schulz, Y., Wehner, P., Opitz, L., Salinas-Riester, G., Bongers, E., van Ravenswaaij-Arts, C., Wincent, J., Schoumans, J., Kohlhase, J., Borchers, A. and Pauli, S. (2104) CHD7, the gene mutated in CHARGE syndrome, regulates genes involved in neural crest cell guidance. Hum. Genet.  (in press).

Müller, D., Cherukuri, P., Henningfeld, K., Poh, C., Wittler,L., Grote, P., Schlüter, O., Schmidt, J., Laborda, J., Bauer, S.R., Brownstone, R.M. and Marquardt, T. (2014) Dlk1 promotes a fast motor neuron biophysical signature required for peak force execution. Science 343, 1264-1266.

Paul, V., Tonchev, A.B., Henningfeld, K.A., Pavlakis, E., Rust, B., Pieler, T. and Stoykova, A. (2014) Scratch2 Modulates Neurogenesis and Cell Migration Through Antagonism of HLH Proteins in the Developing Neocortex. Cereb.Cortex 3, 754-772.

Kanagaraj, P., Gautier-Stein,mA., Riedel, D., Schomburg, C., Cerda, J., Vollack, N. and Dosch, R. (2014) Souffle/Spastizin Controls Secretory Vesicle Maturation during Zebrafish Oogenesis. PLoS Genet. 10, e1004449.


Thelie, A., Desideriol, S., Hanotel, J., Quigley, I., Van Driessche, B., Rodari, A., Borromeo, M., Kricha, S., Lahay, F., Croce, J., Cerda-Moya, G., Fernandez, J., Bolle, B., Lewis, K., Sander, M., Pierani, A., Schubert, M., Johnson, J.E., Kintner, C.R., Pieler, T., Van Lint, C., Henningfeld, K.A., Bellefroid, E.J. and Van Campenhout, C. (2015) Prdm12 specifies V1 interneurons through cross-repressive interactions with Dbx1 and Nkx6 genes in Xenopus. Development, 142, 3416-3428.

Bauermeister, D., Claußen, M. and Pieler, T. (2015) A novel role for Celf1 in vegetal localization during Xenopus oogenesis. Dev. Biol. 405, 214-224

Claußen, M., Lingner, T., Pommerenke, C., Opitz, L., Salinas, G. and Pieler, T. (2015) Global analysis of asymmetric RNA enrichment in oocytes reveals low conservation between closely related Xenopus species. Mol. Biol. Cell E15-02-0115.

Dosch, R. (2015) Next generation mothers: Maternal control of germline Development in zebrafish. Crit Rev Bochem Mol Biol. 50, 54-68.

Riemer, S., Bontems, F., Krishnakumar, P., Gomann, J. and Dosch, R. (2015) A functional Bucky ball-GFP transgene visualizes germ plasm in living zebrafish. Gene Expression Patterns 18, 44-52.