Publications

since 2003

2017

  • Candiello, E., Mishra, R., Schmidt, B., Jahn, O. and Schu, P. (2017) Differential regulation of AP-2/clathrin vesicle uncoating in synaptic plasticity. Sci. Rep. 7, 15781; doi:10.1038/s41598-017-16055-4
  • Zizioli, D., Geumann, C., Kratzke, M., Mishra, R., Borsani, G., Finazzi, D., Candiello, E. and Schu, P. (2017) γ2 and γ1 AP-1 complexes: different essential functions and regulatory mechanisms in clathrin-dependent protein sorting. Eur J Cell Biol 96, 356-368
  • Dib, K., Tikhonova, I., Ivetic, A. and Schu, P. (2017) The cytoplasmic tail of L-selectin interacts with the adaptor-protein complex AP-1 subunit μ1A via a novel basic binding motif. J Biol Chem 292 (16), 6703-6714

2016

  • Candiello, E., Kratzke, M., Wenzel, D., Cassel, D. and Schu, P. (2016) AP-1/σ1A and AP-1/σ1B adaptor-proteins differentially regulate neuronal early endosome maturation via the Rab5/Vps34-pathway. Sci. Rep. 6, 29950; doi: 10.1038/srep29950
  • Seifert, W., Posor, Y., Schu, P., Stenbeck, G., Mundlos, S., Klaassen, S., Nürnberg, P., Haucke, V., Kornak, U. and Kühnisch, J. (2016) The progressive ankylosis protein ANK facilitates clathrin and adaptor-mediated membrane traffic at the trans-Golgi network-to-endosomal interface. Hum Mol Genet 25, (17), 3836-3848

2015

  • Jung, S.Y., Maritzen, T., Wichmann, C., Jing, Z., Neef, A., Revelo, N.H.,  Al-Moyed, H., Meese, S., Wojcik, S.M., Panou, S.M.I., Bulut, H., Schu, P., Ficner, R., Reisinger, E., Rizzoli, S.O., Neef, J., Strenzke, N., Haucke, V. and Moser, T. (2015) Disruption of adaptor protein μ2 (AP-2μ) in cochlear hair cells impairs vesicle reloading of synaptic release sites and hearing. EMBO J. 34, (21), 2686-2702

  • Kratzke, M., Candello, E., Schmidt, B., Jahn, O. and Schu, P. (2015), AP-1/σ1B-Dependent SV protein recycling is regulated in early endosomes and is coupled to AP-2 endocytosis. Mol Neurobiol 52 (1), 142-161

2014

  • Gariano G, Guarienti M, Bresciani R, Borsani G, Carola G, Monti E, Giuliani R, Rezzani R, Bonomini F, Preti A, Schu P*, Zizioli D.* (2014), Analysis of three μ1 AP-1 subunits during zebrafish development. Dev Dyn 243, 299-314 *corresponding authors

  • Baltes, J., Larsen, J.V., Radhakrishnan, K., Geumann, C., Kratzke, M., Petersen, C.M. and Schu, P. (2014), σ1B-adaptin regulates adipogenesis by mediating the sorting of sortilin in adipose tissue. J. Cell Sci. 127, 3477-3487 

2013

  • Radhakrishnan, K., Baltes, J., Creemers, J.W.M. and Schu, P. (2013), TGN morphology and sorting regulated by prolyl-oligopeptidase–like protein PREPL and AP-1 μ1A. J. Cell Sci. 126, 1155-1163 doi:10.1242/jcs.116079

  • Poirier, S., Mayer, G., Murphy, S.R., Garver, W.S., Chang, T.Y., Schu, P.* and Seidah, N.G.* (2013), The cytosolic adaptor AP-1A is essential for the trafficking and function of Niemann-Pick type C proteins. Traffic 14, 458-469; *corresponding authors

  • Agrawal, T., Schu, P. and Medigeshi, G.R. (2013), Adaptor protein complexes-1 and 3 are involved at distinct stages of flavivirus life-cycle. Sci. Rep. 3, 1813, 1-9 doi: 10.1038/srep01813

  • Wieffer M, Uhalte EC, Posor Y, Otten C, Branz K, Schütz I, Mössinger J, Schu P, Abdelilah-Seyfried S, Krauß M, Haucke V. (2013), PI4K2β/AP-1-Based TGN-Endosomal Sorting Regulates Wnt Signaling. Curr Biol 23, 2185-2190

2010

  • Glyvuk N, Tsytsyura Y, Geumann C, D'Hooge R, Hüve J, Kratzke M, Baltes J, Boening D, Klingauf J. and Schu P. (2010), AP-1/σ1B-adaptin mediates endosomal synaptic vesicle recycling, learning and memory. EMBO J. 29, (8), 1318-1330

  • Zizioli, D., Forlanelli, E., Guarienti, M., Nicoli, S., Fanzani, A., Bresciani, R., Borsani, G., Preti, A., Cotelli, F. and Schu, P. (2010), Characterization of the AP-1 μ1A and μ1B adaptins in zebrafish (Danio rerio). Dev. Dyn. 239, 2404-2412

2008

  • Medigeshi, G.R., Krikunova, M., Karthikeyan, R., Wenzel, D., Klingauf, J. and Schu, P. (2008), AP-1 membrane-cytoplasma recycling regulated by μ1A. Traffic 9, 121-132

  • Schu, P. (2008), Aminopeptidase I enzymatic activity. Methods in Enzymology: Autophagy, Chapter 6 Vol 451, 67-79

2007

  • Camus, G., Segura-Morales, C., Molle, D., Lopez-Vergès, S., Begon-Pescia, C., Schu, P., Benarous, R., Bertrand, E., Berlioz-Torrent, C. and Basyuk, E. (2007), The clathrin adaptor complex AP-1 binds HIV-1 and MLV Gag and facilitates their budding. Mol. Biol. Cell. 18, 3193-3203

  • Nielsen, M.S., Gustafsen, C., Madsen, P., Nyengaard, J., Hermey, G., Bakke, O., Mari, M., Schu, P., Pohlmann, R., Dennes, A. and Petersen, C.M. (2007), Sorting of SorLA depends on AP-1, AP-2, GGAs, SNX1 and Vps35. Mol. Cell. Biol. 19, 6842-6851

  • Rollason, R., Korolchuk, V., Hamilton, C., Schu, P. and Banting, G. (2007), Clathrin mediated endocytosis of a lipid raft associated protein is mediated via a dual tyrosine motif. J. Cell Sci. (120) 21, 3850-3858

2005

  • Kyttälä, A., Yliannala, K., Schu, P., Jalanko, A. and Luzio, J.P. (2005), AP-1 and AP-3 facilitate lysosomal targeting of Batten disease protein CLN3 via ist dileucine motif. J. Biol. Chem. 280, 10277-10283

  • Schu, P. (2005), Adaptor Proteins. In Lysosomal Biogenesis 27-36 edited by P. Saftig, Landes Bioscience & Springer.p.,

  • Neubrand, V.E., Will, R.D., Möbius, W., Poustka, A., Wiemann, S., Schu, P., Dotti, C.G., Pepperkok, R. and Simpson, J.C. (2005), γ-BAR, a novel AP-1 interacting protein involved in post-Golgi trafficking. EMBO J. 24, 1122-1133

2004

  • Saint-Pol, A., Yélamos, B., Mills, I., Dugast, M., Tenza, D., Schu, P., Antony, C., McMahon, H.T., Lamaze, C. and Johannes, L. (2004), Clathrin adaptor epsinR is required for retrograde sorting on early endosomal membranes. Dev. Cell 4, 525-538

2003

  • Deneka, M., Neeft, M., Popa, I., van Oort, M., Sprong, H., Oorschot, V., Klumperman, J., Schu, P and van der Sluijs, P. (2003), Rabaptin-5α/rabaptin-4 serves as a linker between rab4 and γ1-adaptin in membrane recycling from endosomes. EMBO J. 22, (11), 2645-2657

  • Lui, W.Y., Collins, B., Hirst, J., Motley, A., Millar, C., Schu, P., Owen, D. and Robinson, M.S. (2003), Binding Partners for the COOH-terminal Appendage Domains of the GGAs and γ-Adaptin. Mol. Biol. Cell 14, 2385-2398

  • Medigeshi, G.R. and Schu, P. (2003), Characterization of the in vitro retrograde transport of MPR46. Traffic 4, 739-753