Publications (since 2015)

2024
Koschel M, Cruz-Zaragoza LD (2024) In organello silencing of mitochondrial gene expression. Methods Enzymol 706, 501-518.

Poerschke S, Oeljeklaus S, Cruz-Zaragoza LD, Schenzielorz A, Dahal D, Hillen HS, Das H, Kremer LS, Valpadashi A, Breuer M, Sattmann J, Richter-Dennerlein R, Warscheid B, Dennerlein S, Rehling P (2024) Identification of TMEM126A as OXA1L-interacting protein reveals cotranslational quality control in mitochondria. Mol Cell , .

2023
Stewart H, Lu Y, O’Keefe S, Valpadashi A, Cruz-Zaragoza LD, Michel HA, Nguyen SK, Carnell GW, Lukhovitskaya N, Milligan R, Adewusi Y, Jungreis I, Lulla V, Matthews DA, High S, Rehling P, Emmott E, Heeney JL, Davidson AD, Edgar JR, Smith GL, Firth AE (2023) The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity. iScience 26, 108080.

Jain N, Gomkale R, Bernhard O, Rehling P, Cruz-Zaragoza LD (2023) A quantitative fluorescence-based approach to study mitochondrial protein import. EMBO Rep , e55760.

Homberg B, Rehling P, and Cruz-Zaragoza LD (2023) The multifaceted mitochondrial OXA insertase. Trends in Cell Biology. DOI: 10.1016/j.tcb.2023.02.001.

2022
Yifrach E, Rudowitz M, Cruz-Zaragoza LD, Tirosh A, Gazi Z, Peleg Y, Kunze M, Eisenstein M, Schliebs W, Schuldiner M, Erdmann R, and Zalckvar E (2022). Determining the targeting specificity of the selective peroxisomal targeting factor Pex9. Biol. Chem. 404, 121-133. DOI: 10.1515/hsz-2022-0116

Nadler F, Lavdovskaia E, Krempler A, Cruz-Zaragoza LD, Dennerlein S, and Richter-Dennerlein R (2022). Human mtRF1 terminates COX1 translation and its ablation induces mitochondrial ribosome-associated quality control. Nature Commun., 13, 6406. DOI: 10.1038/s41467-022-34088-w.

2021
Cruz-Zaragoza LD, Dennerlein S, Linden A, Yousefi R, Lavdovskaia E, Aich A, Falk RR, Gomkale R, Schöndorf T, Bohnsack MT, Aich A, Richter-Dennerlein R, Urlaub H, and Rehling P (2021). An in vitro system to silence mitochondrial gene expression. Cell 184, 5824–5837.e15. DOI: 10.1016/j.cell.2021.09.033.

Gomkale R, Linden A, Neumann P, Schendzielorz AB, Stoldt S, Dybkov O, Kilisch M, Schulz C, Cruz-Zaragoza LD, Schwappach B, Ficner R, Jakobs S, Urlaub H, and Rehling P (2021). Mapping protein interactions in the active TOM-TIM23 supercomplex. Nature Commun. 12, 5715. DOI: 10.1038/s41467-021-26016-1.

2020
Gabay-Maskit S*, Cruz-Zaragoza LD*, Shai N, Eisenstein M, Bibi C, Cohen N, Hansen T, Yifrach E, Harpaz N, Belostotsky R, Schliebs W, Schuldiner M, Erdmann R, and Zalckvar E (2020). A piggybacking mechanism enables peroxisomal localization of the glyoxylate cycle enzyme Mdh2 in yeast. J Cell Sci 133, jcs244376. DOI: 10.1242/jcs.244376.

Gomkale R*, Cruz-Zaragoza LD*, Suppanz I, Guiard B, Montoya J, Callegari S, Pacheu-Grau D, Warscheid B, and Rehling P (2020). Defining the Substrate Spectrum of the TIM22 Complex Identifies Pyruvate Carrier Subunits as Unconventional Cargos. Curr. Biol. 30, 1119–1127.e5. DOI: 10.1016/j.cub.2020.01.024.

Callegari S, Cruz-Zaragoza LD, and Rehling P (2020). From TOM to the TIM23 complex – handing over of a precursor. Biological Chemistry 401, 709–721. DOI: 10.1515/hsz-2020-0101.

2017
Wroblewska JP*, Cruz-Zaragoza LD*, Wei Y, Schummer A, Chuartzman SG, de Boer R, Oeljeklaus S, Schuldiner M,  Zalckvar E, Warscheid B, Erdmann R, and van der Klei IJ. (2017) Saccharomyces cerevisiae cells lacking Pex3 contain membrane vesicles that harbor a subset of peroxisomal membrane proteins. Biochim Biophys Acta Mol. Cell Res. 1864, 1656-1667. DOI: 10.1016/j.bbamcr.2017.05.021.

2016
Effelsberg D*, Cruz-Zaragoza LD*, Tonillo J, Schliebs W, Erdmann R.(2016) Pex9p is a novel yeast peroxisomal import receptor for PTS1-proteins. J. Cell Science. 129, 4057–4066. DOI: 10.1242/jcs.195271.

Galiani S, Waithe D, Reglinski K, Cruz-Zaragoza LD, Garcia E, Clausen MP, Schliebs W, Erdmann R, Eggeling C. (2016) Super resolution microscopy reveals compartmentalization of peroxisomal membrane proteins. J. Biol. Chem. 291, 16948-16962. DOI: 10.1074/jbc.M116.734038.

Chan A, Schummer A, Fischer S, Schröter T, Cruz-Zaragoza LD, Bender J, Drepper F, Oeljeklaus S, Kunau W-H, Girzalsky W, Warscheid B, Erdmann R. (2016) Pex17p-dependent assembly of Pex14p/Dyn2p-subcomplexes of the peroxisomal protein import machinery. Eur J Cell Biol. 95 (12): 585-597. DOI: 10.1016/j.ejcb.2016.10.004.

2015
Effelsberg D, Cruz-Zaragoza LD, Tonillo J, Schliebs W, Erdmann R. (2015) Role of Pex21p for Piggyback Import of Gpd1p and Pnc1p into Peroxisomes of Saccharomyces cerevisiae. J. Biol. Chem. 290, 25333-25342. DOI: 10.1074/jbc.M115.653451.